Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.53 |
| ▸ | MST1R | Q04912 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414365 | 0.88 | MET (0.46) | METMST1RKDRAURKBALK | |
| SCHEMBL2423767 | 0.87 | MET (0.52) | METMST1RKDRAURKBALK | |
| SCHEMBL15387385 | 0.86 | MET (0.52) | METMST1RKDRAURKBALK | |
| SCHEMBL2422550 | 0.86 | MET (0.66) | METMST1RKDRAURKBALK | |
| SCHEMBL3412867 | 0.86 | MET (0.47) | METMST1RKDRAURKBALK | |
| SCHEMBL3414086 | 0.86 | MET (0.47) | METMST1RKDRAURKBALK | |
| SCHEMBL2421986 | 0.84 | MET (0.67) | METMST1RKDRAURKBALK | |
| SCHEMBL2423214 | 0.82 | MET (0.53) | METMST1RKDRAURKBALK | |
| SCHEMBL2424249 | 0.82 | MET (0.51) | METMST1RKDRAURKBALK | |
| SCHEMBL3408021 | 0.81 | MET (0.46) | METMST1RKDRAURKBALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265616-A1 | FURO-AND THIENO[3,2-C]PYRIDINES | OSI Pharmaceuticals, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009100282-A1 | FURO-AND THIENO[3,2-C] PYRIDINES | OSI PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |