⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888555 | 0.76 | — | — | |
| SCHEMBL2643098 | 0.76 | — | — | |
| SCHEMBL2523804 | 0.76 | — | — | |
| SCHEMBL771164 | 0.73 | — | — | |
| SCHEMBL4864412 | 0.71 | — | — | |
| SCHEMBL770087 | 0.71 | — | — | |
| SCHEMBL12961895 | 0.71 | — | — | |
| SCHEMBL7688618 | 0.71 | — | — | |
| SCHEMBL769937 | 0.71 | — | — | |
| SCHEMBL13536861 | 0.70 | NFKB1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160256447-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2016-09-08 | — | — | US | disclosed |
| US-9181219-B2 | Compounds of modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140011840-A1 | Compounds of Modulating TRPV3 Function | HYDRA BIOSCIENCES, INC. (US) | 2014-01-09 | — | — | US | disclosed |
| US-8389546-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120015979-A1 | Compounds for Modulating TRPV3 Function | Hydra Biosciences, Inc, (US) | 2012-01-19 | — | — | US | disclosed |
| US-7998980-B2 | Transient Receptor Potential channel modulators; N-(2-pyridinyloxy- or 2-pyridinylthio-alkanoyl)quinolines; acute or chronic pain, sensitivity, burns, diabetic neuropathy, psoriasis, eczema, dermatitis, post-herpetic neuralgia, migraine, incontinence, fever, hot flashes, osteoarthritis; depilatories | HYDRA BIOSCIENCES, INC. (US) | 2011-08-16 | — | — | US | disclosed |
| US-20080146611-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC. (US) | 2008-06-19 | — | — | US | disclosed |
| WO-2008033564-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC. (US) | 2008-03-20 | — | — | WO | disclosed |