Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 4/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471990 | 0.89 | CYP2C19 (0.58) | CYP2C19MGLLFNTAFNTBMALT1 | |
| SCHEMBL2472073 | 0.79 | SMARCA2 (0.52) | SMARCA2SMARCA4KMT2AJAK1 | |
| SCHEMBL1553389 | 0.73 | ROCK2 (0.61) | KMT2ATDP1 | |
| SCHEMBL22644367 | 0.72 | SMARCA2 (0.50) | SMARCA2SMARCA4JAK1 | |
| SCHEMBL12833234 | 0.72 | RXFP1 (0.63) | CYP2C19POLBHSD17B10MAPT | |
| SCHEMBL17796425 | 0.72 | TYK2 (0.59) | SMARCA2SMARCA4KMT2AJAK1 | |
| Hydrochloric Acid SCHEMBL27414471 | 0.72 | ROCK2 (0.60) | KMT2ATDP1 | |
| SCHEMBL1554428 | 0.71 | PTPN1 (0.67) | MGLLPOLBKMT2AMAPTTDP1 | |
| SCHEMBL1553796 | 0.69 | PTPN1 (0.76) | CYP2C19MGLLTDP1 | |
| SCHEMBL1554138 | 0.69 | PTPN1 (0.60) | MGLLPOLBKMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048673-A1 | MODULATION OF CELLULAR DIFFERENTIATION AND USES THEREFOR | MURDOCH CHILDRENS RESEARCH INSTITUTE (AU) | 2010-05-06 | — | — | WO | disclosed |