SCHEMBL3418358

SCHEMBL3418358

CCCCCCCCCCC(C#N)[Si](OC)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.34
LMNA P02545 2/20 0.33
TSHR P16473 2/20 0.33
DNM1 Q05193 2/20 0.32
SMPD1 P17405 3/20 0.32
OPRM1 P35372 1/20 0.31
THRB P10828 1/20 0.31
FDPS P14324 3/20 0.31
GPR84 Q9NQS5 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3443203 1.00 ZDHHC7 (0.34) ZDHHC7LMNATSHRDNM1SMPD1
SCHEMBL28797292 0.98 TSHR (0.34) ZDHHC7LMNATSHROPRM1
SCHEMBL29001368 0.78
SCHEMBL3415771 0.76 TSHR (0.36) LMNATSHRDNM1OPRM1THRB
SCHEMBL29032446 0.74
SCHEMBL28718391 0.74 ZDHHC7 (0.37) ZDHHC7LMNATSHRDNM1SMPD1
SCHEMBL22721264 0.74 ZDHHC7 (0.37) ZDHHC7LMNATSHRDNM1SMPD1
SCHEMBL21750612 0.74 ZDHHC7 (0.37) ZDHHC7LMNATSHRDNM1SMPD1
SCHEMBL28510570 0.74 ZDHHC7 (0.37) ZDHHC7LMNATSHRDNM1SMPD1
SCHEMBL6696575 0.74 TSHR (0.37) LMNATSHRDNM1OPRM1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016016042-A1 AGROCHEMICAL SUSPOEMULSION COMPRISING HYDROPHOBIC MODIFIED SILICA PARTICLES BASF SE (DE) 2016-02-04 WO disclosed
WO-2016008696-A1 AGROCHEMICAL OIL-IN-WATER EMULSION COMPRISING SILICA PARTICLES AND WATER-SOLUBLE NONIONIC EMULSIFIER BASF SE (DE) 2016-01-21 WO disclosed
EP-2205644-A1 METHOD FOR PRODUCING AN AQUEOUS COMPOSITE-PARTICLE DISPERSION BASF SE (DE) 2010-07-14 EP disclosed
WO-2009053317-A1 METHOD FOR PRODUCING AN AQUEOUS COMPOSITE-PARTICLE DISPERSION BASF SE (DE) 2009-04-30 WO disclosed
EP-1937328-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2008-07-02 EP disclosed
WO-2007041972-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2007-04-19 WO disclosed
EP-1546250-A2 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA Dow Corning Corporation (US) 2005-06-29 EP disclosed
WO-2004024812-A2 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA DOW CORNING CORPORATION (US) 2004-03-25 WO disclosed
US-20030172867-A1 Preparation of nano-sized crystals NUCCON TECHNOLOGIES INC. 2003-09-18 US disclosed
WO-2003057949-A1 PREPARATION OF NANO-SIZED CRYSTALS NUCCON TECHNOLOGIES INC. (US) 2003-07-17 WO disclosed