SCHEMBL6696575

SCHEMBL6696575

CCCCCC(C#N)[Si](Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
OPRM1 P35372 1/20 0.34
LMNA P02545 1/20 0.32
DNM1 Q05193 2/20 0.31
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3415771 0.98 TSHR (0.36) TSHROPRM1LMNADNM1FDPS
SCHEMBL28797292 0.75 TSHR (0.34) TSHROPRM1LMNA
SCHEMBL5709051 0.74
SCHEMBL3443203 0.74 ZDHHC7 (0.34) TSHROPRM1LMNADNM1FDPS
SCHEMBL3418358 0.74 ZDHHC7 (0.34) TSHROPRM1LMNADNM1FDPS
SCHEMBL8411146 0.74 OPRM1 (0.35) TSHROPRM1LMNADNM1FDPS
SCHEMBL8413567 0.72 TSHR (0.36) TSHROPRM1LMNADNM1FDPS
SCHEMBL8411253 0.71 FDPS (0.35) TSHROPRM1LMNADNM1FDPS
SCHEMBL671491 0.71 OPRM1 (0.43) TSHROPRM1LMNADNM1FDPS
SCHEMBL1131040 0.71 TSHR (0.48) TSHROPRM1LMNADNM1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040261455-A1 Process for preparation of glass optical element HOYA CORPORATION (JP) 2004-12-30 US disclosed
CN-1552649-A Method of manufacturing glass optical device HOYA��ʽ���� 2004-12-08 CN disclosed
US-20040206116-A1 Method of preparation of glass articles HOYA CORPORATION (JP) 2004-10-21 US disclosed
US-20040177648-A1 Glass material for molding, method of manufacturing same, and method of manufacturing glass articles using same HOYA CORPORATION (JP) 2004-09-16 US disclosed