Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL15659730 | 1.00 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10USP2 | |
| Propylene Glycol SCHEMBL7191897 | 0.95 | TDP1 (0.50) | TDP1ALDH1A1TSHRHSD17B10 | |
| Propylene Glycol SCHEMBL11184695 | 0.95 | TDP1 (0.50) | TDP1ALDH1A1TSHRHSD17B10 | |
| Propylene Glycol SCHEMBL4936361 | 0.94 | TDP1 (0.62) | TDP1ALDH1A1TSHRHSD17B10USP2 | |
| Propylene Glycol SCHEMBL35797 | 0.94 | TDP1 (0.62) | TDP1ALDH1A1TSHRHSD17B10USP2 | |
| Propylene Glycol SCHEMBL18285762 | 0.94 | TDP1 (0.62) | TDP1ALDH1A1TSHRHSD17B10USP2 | |
| Propylene Glycol SCHEMBL6135352 | 0.92 | TDP1 (0.59) | TDP1ALDH1A1TSHRHSD17B10USP2 | |
| Propylene Glycol SCHEMBL8231638 | 0.92 | TDP1 (0.59) | TDP1ALDH1A1TSHRHSD17B10USP2 | |
| Propylene Glycol SCHEMBL93425 | 0.89 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10USP2 | |
| Propylene Glycol SCHEMBL28174906 | 0.89 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112512-A1 | THIOL-CONTAINING ALCOHOLS FOR GENERATING NITRIC OXIDE AND METHODS OF FORMING THE SAME | STERILE STATE LLC (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112667-A1 | THIOLACTONE-DERIVED COMPOUNDS FOR GENERATING NITRIC OXIDE AND METHODS OF FORMING THE SAME | STERILE STATE, LLC (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024009914-A1 | LAMINATE | ダイキン工業株式会社 | 2024-01-11 | — | — | WO | disclosed |
| WO-2023248919-A1 | OPTICAL FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE | 株式会社トッパンＴＯＭＯＥＧＡＷＡオプティカルフィルム | 2023-12-28 | — | — | WO | disclosed |
| WO-2023243655-A1 | POLARIZING PLATE AND DISPLAY DEVICE USING SAME | 株式会社トッパンＴＯＭＯＥＧＡＷＡオプティカルフィルム | 2023-12-21 | — | — | WO | disclosed |
| WO-2023223785-A1 | OPTICAL LAMINATE AND IMAGE DISPLAY DEVICE INCLUDING SAME | 凸版印刷株式会社 | 2023-11-23 | — | — | WO | disclosed |
| WO-2023224104-A1 | OPTICAL LAMINATE AND IMAGE DISPLAY DEVICE USING SAME | 凸版印刷株式会社 | 2023-11-23 | — | — | WO | disclosed |
| WO-2023219811-A1 | NITRIC OXIDE PRECURSORS AND MULTI-COMPONENT COMPOSITIONS FOR FORMING THE SAME | STERILE STATE, LLC (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023210653-A1 | SURFACE TREATMENT AGENT | ダイキン工業株式会社 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023210654-A1 | FLUOROPOLYETHER GROUP-CONTAINING OXYALKYLENE AMIDE COMPOUND | ダイキン工業株式会社 | 2023-11-02 | — | — | WO | disclosed |
| WO-2020203666-A1 | FLUOROPOLYETHER GROUP-CONTAINING COMPOUND | ダイキン工業株式会社 | 2020-10-08 | — | — | WO | disclosed |
| WO-2020203676-A1 | FLUOROPOLYETHER-GROUP-CONTAINING COMPOUND | ダイキン工業株式会社 | 2020-10-08 | — | — | WO | disclosed |
| WO-2019189171-A1 | HEAT-DISSIPATING INSULATING RESIN COMPOSITION, AND PRINTED WIRING BOARD IN WHICH SAME IS USED | 太陽インキ製造株式会社 | 2019-10-03 | — | — | WO | disclosed |
| US-20190203068-A1 | DISPERSANTS, COATING COMPOSITIONS INCLUDING DISPERSANTS, AND METHODS OF FORMING THE SAME | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2019-07-04 | — | — | US | disclosed |
| US-8211970-B2 | Aqueous pigment dispersions | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-03 | — | — | US | disclosed |
| EP-2125980-B1 | AQUEOUS PIGMENT DISPERSIONS | DU PONT (US) | 2010-12-22 | — | — | EP | disclosed |
| US-20100036045-A1 | AQUEOUS PIGMENT DISPERSIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-11 | — | — | US | disclosed |
| EP-2125980-A1 | AQUEOUS PIGMENT DISPERSIONS | E. I. Du Pont de Nemours and Company (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008103356-A1 | AQUEOUS PIGMENT DISPERSIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-28 | — | — | WO | disclosed |
| US-5936026-A | GRAFT POLYMER PIGMENTED BASECOAT OR CLEAR COAT FOR AUTOMOBILE FINISHES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-08-10 | — | — | US | disclosed |