Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL18285762 | 1.00 | TDP1 (0.62) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL4936361 | 1.00 | TDP1 (0.62) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL8231638 | 0.97 | TDP1 (0.59) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL6135352 | 0.97 | TDP1 (0.59) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL28174906 | 0.94 | TDP1 (0.56) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL15659730 | 0.94 | TDP1 (0.56) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL3418653 | 0.94 | TDP1 (0.56) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL93425 | 0.94 | TDP1 (0.56) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Glycerin SCHEMBL2236339 | 0.92 | TDP1 (0.53) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Benzene SCHEMBL2865296 | 0.92 | TDP1 (0.53) | TDP1TSHRALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 27992 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260147279-A1 | DEVELOPER COMPOSITION FOR METAL-CONTAINING PHOTORESIST, AND METHOD OF FORMING PATTERNS INCLUDING DEVELOPING METHOD USING THE COMPOSITION | SAMSUNG SDI CO., LTD. (KR) | 2026-05-28 | — | — | US | claimed |
| CN-122095027-A | Modified maleated natural oil-based reaction products and slurry compositions containing the same | — | 2026-05-26 | — | — | CN | claimed |
| CN-122084338-A | N-nitrosamine mixed solution standard substance and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-118117169-B | Special additive for electrolyte, electrolyte and lithium ion battery | TIANMU LAKE INSTITUTE OF ADVANCED ENERGY STORAGE TECHNOLOGIES Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122084340-A | N-nitrosonornicotine (NNN) purity standard substance, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079957-A | N-nitroso-pseudoscouring (NAB) purity standard substance and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122084339-A | Purity standard substance for tobacco, tobacco products and smoke, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-121673935-B | Strippable coating composition with hot-pressing Fresnel lens effect and preparation method thereof | SHANGHAI GAOBANG PRINTING MATERIAL Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122060355-A | Coating with covering and thermal-changing characteristics, thermosensitive color-developing material, preparation process and application | 山东世纪阳光纸业集团有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-118685108-B | Anti-dazzle antibacterial coating liquid and preparation method thereof, anti-dazzle antibacterial coating, anti-dazzle antibacterial optical film and polaroid and preparation method thereof | 宁波惠之星新材料科技股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| EP-0078615-A1 | Process for preparing glycol ethers | TEXACO DEVELOPMENT CORPORATION (US) | 1983-05-11 | — | — | EP | claimed |
| US-4322550-A | HIGH-SPEED SOLVENT EXTRACTION FROM AN AQUEOUS SOLUTION | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-30 | — | — | US | claimed |
| US-4308184-A | TEXTILES; ADHESION, SOFTNESS, SOLVENT RESISTANCE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-29 | — | — | US | claimed |
| US-4272526-A | HYPNOTICS | MACARTHYS PHARMACEUTICALS LIMITED (GB) | 1981-06-09 | — | — | US | claimed |
| US-4230609-A | INTERPOLYMER OF A HYDROPHOBIC MONOMER; AN ACRYLATE, VINYL ETHER, OR DIENE; AND HYDROPHILIC MONOMER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| US-4227996-A | FROTH FLOTATION, POLYAMINE CATIONIC COLLECTOR | CELANESE CORPORATION (US) | 1980-10-14 | — | — | US | claimed |
| EP-0007159-A1 | A chloral derivative; method for preparing this derivative and a therapeutic composition containing this derivative | MACARTHYS PHARMACEUTICALS LIMITED (GB) | 1980-01-23 | — | — | EP | claimed |
| US-4124555-A | FILM FORMING | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-11-07 | — | — | US | claimed |
| US-4077858-A | Completely polymerized ultraviolet cured coatings | CELANESE CORPORATION (US) | 1978-03-07 | — | — | US | claimed |
| US-4009997-A | Levelling auxiliaries for acid dyes | BASF AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | claimed |