Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Benzylcarbamate SCHEMBL1136818 | 0.90 | PLAU (0.70) | PLAUHTTHDAC1HDAC2HDAC3 | |
| Benzyl Benzylcarbamate SCHEMBL9998166 | 0.89 | PLAU (0.68) | PLAUHTTHDAC1HDAC2HDAC3 | |
| Benzyl Benzylcarbamate SCHEMBL28413454 | 0.89 | PLAU (0.68) | PLAUHTTHDAC1HDAC2HDAC3 | |
| Benzyl Benzylcarbamate SCHEMBL19810513 | 0.89 | PLAU (0.68) | PLAUHTTHDAC1HDAC2HDAC3 | |
| SCHEMBL191161 | 0.87 | PLAU (0.68) | PLAUHTTHDAC1HDAC2HDAC3 | |
| SCHEMBL992896 | 0.87 | PLAU (0.60) | PLAUHTTHDAC1HDAC2HDAC3 | |
| SCHEMBL20047179 | 0.86 | PLAU (0.66) | PLAUHTTHDAC1HDAC2HDAC3 | |
| Benzyl Benzylcarbamate SCHEMBL29011837 | 0.85 | PLAU (0.65) | PLAUHTTHDAC1HDAC2HDAC3 | |
| SCHEMBL192484 | 0.84 | PLAU (0.64) | PLAUHTTHDAC1HDAC2HDAC3 | |
| SCHEMBL17064147 | 0.84 | PLAU (0.64) | PLAUHTTHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240206-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089022-A1 | N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2009-07-16 | — | — | WO | disclosed |