Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA7 | P43166 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 4/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418940 | 0.88 | CA12 (0.43) | CA12CA7CA1CA2CA9 | |
| SCHEMBL31423810 | 0.88 | CA12 (0.43) | CA12CA7CA1CA2CA9 | |
| SCHEMBL10778120 | 0.82 | AKR1C4 (0.46) | CA12CA7CA1CA2CA9 | |
| SCHEMBL6671367 | 0.80 | TTR (0.50) | CA12CA7CA1CA2CA9 | |
| SCHEMBL138029 | 0.77 | CA12 (0.36) | CA12CA7CA1CA2CA9 | |
| SCHEMBL6261348 | 0.77 | CA12 (0.38) | CA12CA7CA1CA2CA9 | |
| Pyromellitic Acid SCHEMBL10536463 | 0.75 | CA12 (0.56) | CA12CA7CA1CA2CA9 | |
| SCHEMBL10617957 | 0.73 | TYMS (0.43) | CA12CA7CA1CA2CA9 | |
| SCHEMBL8125010 | 0.72 | MAPT (0.45) | CA12CA7CA1CA2CA9 | |
| SCHEMBL8174301 | 0.72 | TTR (0.47) | CA12CA7CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835911-B1 | Compositions of poly(phenylene ether) and polyamide resins | GEN ELECTRIC (US) | 2001-05-09 | — | — | EP | claimed |
| EP-0435023-B1 | Method for removing volatile substances from polyphenylene ether resin blends | GEN ELECTRIC (US) | 1998-06-10 | — | — | EP | claimed |
| EP-0583958-B1 | Polyimide/aliphatic polyester copolymers | EXXON RESEARCH ENGINEERING CO (US) | 1996-10-02 | — | — | EP | claimed |
| EP-0395994-B1 | Polyphenylene ether-polyamide composition | GEN ELECTRIC (US) | 1995-01-11 | — | — | EP | claimed |
| EP-0363584-B1 | Silylation method | GEN ELECTRIC (US) | 1994-09-14 | — | — | EP | claimed |
| EP-0284873-B1 | SILYLATION METHOD | GENERAL ELECTRIC COMPANY (US) | 1993-09-01 | — | — | EP | claimed |
| EP-0258421-B1 | IMPACT MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1992-08-12 | — | — | EP | claimed |
| EP-0195815-B1 | FUNCTIONALIZED POLYPHENYLENE ETHERS AND BLENDS WITH POLYAMIDES | GENERAL ELECTRIC COMPANY (US) | 1991-12-11 | — | — | EP | claimed |
| EP-0261574-B1 | CURABLE CROSS-LINKED POLYPHENYLENE ETHER INTERPENETRATING POLYMER NETWORK COMPOSITIONS AND PROCESS | GENERAL ELECTRIC COMPANY (US) | 1991-11-13 | — | — | EP | claimed |
| EP-0264623-B1 | CURABLE LINEAR POLYPHENYLENE ETHER INTERPENETRATING POLYMER NETWORK COMPOSITIONS AND PROCESS | GENERAL ELECTRIC COMPANY (US) | 1991-11-06 | — | — | EP | claimed |
| EP-0279196-B1 | POLYPHENYLENE ETHER-POLYCARBONATE COPOLYMERS AND METHOD OF PREPARATION | GENERAL ELECTRIC COMPANY (US) | 1991-11-06 | — | — | EP | claimed |
| EP-0270809-B1 | FUNCTIONALIZED THERMOPLASTIC POLYMERS, BLENDS PREPARED THEREFROM, AND METHODS FOR PREPARING BLENDS | GENERAL ELECTRIC COMPANY (US) | 1991-03-13 | — | — | EP | claimed |
| EP-0017422-B1 | THERMOPLASTIC POLYAMIDEIMIDE COPOLYMERS AND METHOD OF PREPARATION | TORAY INDUSTRIES, INC. (JP) | 1983-11-30 | — | — | EP | claimed |