Mescaline

Mescaline

SCHEMBL34190

COc1cc(CCN)cc(OC)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 1.00
HTR2C P28335 2/20 1.00
HTR2B P41595 2/20 1.00
CYP19A1 P11511 1/20 0.67
KDM4E B2RXH2 1/20 0.62
ATM Q13315 1/20 0.62
AOC3 Q16853 2/20 0.61
PTGS2 P35354 1/20 0.59
TAAR1 Q96RJ0 2/20 0.58
TUBB4A P04350 2/20 0.58
TUBB P07437 2/20 0.58
TUBA3C P0DPH7 2/20 0.58
TUBA1B P68363 2/20 0.58
TUBA4A P68366 2/20 0.58
TUBB4B P68371 2/20 0.58
TUBB3 Q13509 2/20 0.58
TUBB2A Q13885 2/20 0.58
TUBB8 Q3ZCM7 2/20 0.58
TUBA3E Q6PEY2 2/20 0.58
TUBA1A Q71U36 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mescaline SCHEMBL25170531 1.00 HTR2A (1.00) HTR2AHTR2CHTR2BCYP19A1KDM4E
Mescaline SCHEMBL25272711 0.98 HTR2A (0.96) HTR2AHTR2CHTR2BCYP19A1KDM4E
Mescaline SCHEMBL3219304 0.98 HTR2A (0.96) HTR2AHTR2CHTR2BCYP19A1KDM4E
Mescaline SCHEMBL6056084 0.92 HTR2A (0.85) HTR2AHTR2CHTR2BCYP19A1KDM4E
SCHEMBL20970881 0.89 HTR2A (0.81) HTR2AHTR2CHTR2BCYP19A1KDM4E
SCHEMBL30261185 0.89 HTR2A (0.81) HTR2AHTR2CHTR2BCYP19A1KDM4E
Mescaline SCHEMBL7637450 0.89 HTR2A (0.79) HTR2AHTR2CHTR2BCYP19A1KDM4E
Mescaline SCHEMBL31079671 0.88 HTR2A (0.79) HTR2AHTR2CHTR2BCYP19A1KDM4E
SCHEMBL31347535 0.88 HTR2A (0.79) HTR2AHTR2CHTR2BCYP19A1KDM4E
SCHEMBL11291141 0.88 HTR2A (0.79) HTR2AHTR2CHTR2BCYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6832 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132413-A1 AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RES FOUNDATION (US) 2026-05-14 US claimed
EP-4731211-A1 ALLYL- AND PROPARGYLAMINE-TYPE PHENETHYLAMINES AND TRYPTAMINES FOR TREATING MEDICAL DISORDERS Definium Therapeutics US, Inc. (US) 2026-04-29 EP claimed
EP-4728531-A1 BIOADAPTIVE THERAPEUTIC ENVIRONMENTS Therapod LLC (US) 2026-04-22 EP claimed
US-12594388-B2 Device to deliver a predetermined amount of a substance to a natural orifice of the body APTARGROUP, INC. (US) 2026-04-07 US claimed
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness DRESDNER JR KARL P (US) 2026-04-02 US claimed
US-20260083759-A1 Combinations Comprising Psychedelics for the Treatment of Schizophrenia and Other Neuropsychiatric and Neurologic Disorders HADASIT MED RES SERVICE (IL) 2026-03-26 US claimed
US-20260080800-A1 COMBINATION THERAPY WITH DIGITAL THERAPEUTICS FOR IMPROVED IMMUNE FUNCTION REMEPY HEALTH LTD (IL) 2026-03-19 US claimed
US-20260053878-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS NEURAL THERAPEUTICS INC (CA) 2026-02-26 US claimed
EP-4358962-B1 TREATMENT FOR AUTOIMMUNE DISEASES COMPRISING NALTREXONE OR A METABOLITE OR ANALOG THEREOF, A CANNABINOID AND A 5-HT RECEPTOR AGONIST LDN PHARMA LTD (GB) 2026-02-04 EP claimed
US-12514883-B2 Compositions and methods for modulating lipid and steroid metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 US claimed
WO-2002022801-A2 MAMMALIAN RECEPTOR GENES AND USES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2002-03-21 WO claimed
WO-2002005851-A2 ENHANCEMENT OF THE ACTION OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM AGENTS PITMY INTERNATIONAL N.V. (AN) 2002-01-24 WO claimed
US-6150387-A Heterocyclic carboxamide compounds effective in the treatment of drug abuse RHONE-POULENC RORER S.A. (FR) 2000-11-21 US claimed
US-6126924-A Light responsive self-tanning products and methods for use SCALES-MEDEIROS VIRGINIA A (US) 2000-10-03 US claimed
JP-2000504681-A 2000-04-18 JP claimed
EP-0879054-A1 APPLICATION OF PYRROLIDINE DERIVATIVES TO THE PREPARATION OF MEDICAMENTS INTENDED TO THE TREATMENT OF DRUG ABUSE Aventis Pharma S.A. (FR) 1998-11-25 EP claimed
WO-1997029121-A1 APPLICATION OF UREIDOACETAMIDES TO THE PREPARATION OF MEDICAMENTS INTENDED TO THE TREATMENT OF THE ABUSE OF DRUGS OR SUBSTANCES GIVING RISE TO PHARMACOMANIA OR TO AN EXCESSIVE USE RHONE-POULENC RORER S.A. (FR) 1997-08-14 WO claimed
WO-1997028800-A1 USE OF THIAZOLIDINE DERIVATIVES TO PREPARE DRUGS FOR TREATING DRUGS ABUSE RHONE-POULENC RORER S.A. (FR) 1997-08-14 WO claimed
WO-1997028798-A1 APPLICATION OF PYRROLIDINE DERIVATIVES TO THE PREPARATION OF MEDICAMENTS INTENDED TO THE TREATMENT OF DRUG ABUSE RHONE-POULENC RORER S.A. (FR) 1997-08-14 WO claimed
WO-1997028799-A1 APPLICATION OF PYRROLIDINE DERIVATIVES TO THE PREPARATION OF MEDICAMENTS FOR THE TREATMENT OF DRUG ABUSE RHONE POULENC RORER S.A. (FR) 1997-08-14 WO claimed