SCHEMBL11291141

SCHEMBL11291141

COc1cc(CCN)cc(C)c1OC

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.79
HTR2C P28335 2/20 0.79
HTR2B P41595 2/20 0.79
KDM4E B2RXH2 1/20 0.55
ATM Q13315 1/20 0.55
CYP19A1 P11511 1/20 0.54
TAAR1 Q96RJ0 3/20 0.51
TSHR P16473 2/20 0.51
MAPK1 P28482 1/20 0.51
AOC3 Q16853 2/20 0.50
CYP1A2 P05177 2/20 0.50
LMNA P02545 2/20 0.50
GLA P06280 1/20 0.50
TUBB4A P04350 1/20 0.47
TUBB P07437 1/20 0.47
TUBA3C P0DPH7 1/20 0.47
TUBA1B P68363 1/20 0.47
TUBA4A P68366 1/20 0.47
TUBB4B P68371 1/20 0.47
TUBB3 Q13509 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mescaline SCHEMBL25170531 0.88 HTR2A (1.00) HTR2AHTR2CHTR2BKDM4EATM
Mescaline SCHEMBL34190 0.88 HTR2A (1.00) HTR2AHTR2CHTR2BKDM4EATM
Mescaline SCHEMBL3219304 0.86 HTR2A (0.96) HTR2AHTR2CHTR2BKDM4EATM
Mescaline SCHEMBL25272711 0.86 HTR2A (0.96) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL26065134 0.85 HTR2A (0.62) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL12172998 0.85 HTR2A (0.55) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL17225934 0.83 PTGS2 (0.53) HTR2AHTR2CHTR2BCYP19A1AOC3
Mescaline SCHEMBL6056084 0.81 HTR2A (0.85) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL31347535 0.81 HTR2A (0.79) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL1159408 0.81 HTR2A (0.79) HTR2AHTR2CHTR2BKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023164178-A2 METHODS FOR PREPARING MESCALINE JOURNEY COLAB CORP. (US) 2023-08-31 WO disclosed
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed
CN-105418601-A Tetrahydrocoptisine derivative and applications thereof CHENGDU BEISI KAIRUI BIOLOGICAL TECH CO LTD 2016-03-23 CN disclosed
EP-0004794-B1 SUBSTITUTED BENZAZEPINES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SMITHKLINE BECKMAN CORPORATION (US) 1982-04-28 EP disclosed
EP-0004794-A2 Substituted benzazepines, processes for preparing them and pharmaceutical compositions containing them SMITHKLINE BECKMAN CORPORATION (US) 1979-10-17 EP disclosed
US-4171359-A DOPAMINERGIC ACTIVITY SMITHKLINE CORPORATION (US) 1979-10-16 US disclosed