SCHEMBL3419224

SCHEMBL3419224

Clc1ccc(N(c2ccccc2)c2ccc(N(c3ccccc3)c3ccc(Cl)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
CYP1A2 P05177 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MAPT P10636 2/20 0.56
KDM4E B2RXH2 2/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
TSHR P16473 1/20 0.53
CRHBP P24387 2/20 0.46
CRHR2 Q13324 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ATM Q13315 1/20 0.46
TLR9 Q9NR96 1/20 0.46
LMNA P02545 2/20 0.44
CYP2A6 P11509 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13050042 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
SCHEMBL6350639 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
SCHEMBL1133413 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
Hydrochloric Acid SCHEMBL29208948 0.97 ALDH1A1 (0.54) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
SCHEMBL1702246 0.93 CYP1A2 (0.64) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
SCHEMBL20871977 0.93 CYP1A2 (0.64) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
SCHEMBL14340293 0.93 CYP1A2 (0.64) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
SCHEMBL16837503 0.93 CYP1A2 (0.64) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
Chlorobenzene SCHEMBL29214764 0.92 TSHR (0.65) ALDH1A1CYP1A2TDP1L3MBTL1MAPT
SCHEMBL23358103 0.91 CYP1A2 (0.68) ALDH1A1CYP1A2TDP1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106654234-A Lithium battery anode material and preparation method thereof 深圳市斯诺实业发展股份有限公司 2017-05-10 CN disclosed
US-7670506-B1 Photoactive compositions for liquid deposition E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-02 US disclosed
EP-0918811-B1 POLY(ARYLAMINES) AND FILMS THEREOF DOW CHEMICAL CO (US) 2000-12-27 EP disclosed
US-5948552-A Heat-resistant organic electroluminescent device HEWLETT-PACKARD COMPANY (US) 1999-09-07 US disclosed
EP-0918811-A1 POLY(ARYLAMINES) AND FILMS THEREOF THE DOW CHEMICAL COMPANY (US) 1999-06-02 EP disclosed
US-5728801-A FILMS USEFUL AS CHARGE TRANSPORT LAYERS IN LIGHT-EMITTING DIODES THE DOW CHEMICAL COMPANY (US) 1998-03-17 US disclosed
EP-0827366-A2 Heat-resistant organic electroluminescent device Hewlett-Packard Company (US) 1998-03-04 EP disclosed
WO-1998006773-A1 POLY(ARYLAMINES) AND FILMS THEREOF THE DOW CHEMICAL COMPANY (US) 1998-02-19 WO disclosed
WO-1997033193-A2 CROSS-LINKABLE OR CHAIN EXTENDABLE POLYARYLPOLYAMINES AND FILMS THEREOF THE DOW CHEMICAL COMPANY (US) 1997-09-12 WO disclosed