Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBASH3B | Q8TF42 | 1/20 | 0.70 |
| ▸ | TACR1 | P25103 | 6/20 | 0.49 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666855 | 0.88 | UBASH3B (0.79) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL17268610 | 0.87 | UBASH3B (0.75) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL2859201 | 0.87 | UBASH3B (0.69) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL16666555 | 0.86 | UBASH3B (0.76) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL16666556 | 0.85 | UBASH3B (0.71) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL16666489 | 0.84 | UBASH3B (0.74) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL16666648 | 0.84 | UBASH3B (0.74) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL16666451 | 0.84 | UBASH3B (0.74) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL16666589 | 0.84 | UBASH3B (0.68) | UBASH3BTACR1CCKBRKDM4EALDH1A1 | |
| SCHEMBL16666339 | 0.84 | UBASH3B (0.68) | UBASH3BTACR1CCKBRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706383-B1 | Amine salt of carbostyril derivative useful for the treatment of, inter alia, gastric ulcer | OTSUKA PHARMA CO LTD (JP) | 2015-07-22 | — | — | EP | disclosed |
| EP-2253619-A1 | Amine salt of carbostyril derivative | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |