Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBASH3B | Q8TF42 | 1/20 | 0.75 |
| ▸ | TACR1 | P25103 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | F11 | P03951 | 2/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666855 | 0.91 | UBASH3B (0.79) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL16666555 | 0.89 | UBASH3B (0.76) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL16666339 | 0.89 | UBASH3B (0.68) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL16666556 | 0.88 | UBASH3B (0.71) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL16666447 | 0.88 | UBASH3B (0.68) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL16666648 | 0.88 | UBASH3B (0.74) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL16666489 | 0.88 | UBASH3B (0.74) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL16666451 | 0.88 | UBASH3B (0.74) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL3420093 | 0.87 | UBASH3B (0.70) | UBASH3BTACR1KDM4EALDH1A1PKM | |
| SCHEMBL9294082 | 0.87 | UBASH3B (0.72) | UBASH3BTACR1KDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180125986-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | SATYAM APPARAO (IN) | 2018-05-10 | — | — | US | disclosed |
| US-9844599-B2 | Nitric oxide releasing produgs of therapeutic agents | SATYAM APPARAO (IN) | 2017-12-19 | — | — | US | disclosed |
| US-20150328323-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | SATYAM APPARAO (IN) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125986-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | NOS2, NOS1, NOS3 | UBASH3B 4529/4885TACR1 249/4885KDM4E 3441/4885 |
| US-20150328323-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | NOS2, NOS1, PTGIS | UBASH3B 4502/4885TACR1 269/4885KDM4E 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.