Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11284328 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL129827 | 0.96 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL24250493 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL24250496 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL21906270 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL24250478 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| SCHEMBL24250483 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| Hydrochloric Acid SCHEMBL11575944 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| Hydrochloric Acid SCHEMBL30679204 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 | |
| Hydrochloric Acid SCHEMBL11575940 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRLOXLOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256262-A1 | RESIN COMPOSITION AND MOLDED BODY USING THE SAME | UNITIKA LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20090291291-A1 | FLAME RETARDANT PRESSURE SENSITIVE ADHESIVE | AVERY DENNISON CORPORATION (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2008105887-A2 | FLAME RETARDANT ADHESIVE FILM | AVERY DENNISON CORPORATION (US) | 2008-09-04 | — | — | WO | disclosed |
| US-7052630-B2 | Resin additive composition and process for producing the same | AJINOMOTO CO., INC. (JP) | 2006-05-30 | — | — | US | disclosed |
| EP-1253168-B1 | RESIN ADDITIVE COMPOSITION AND PROCESS FOR PRODUCING THE SAME | AJINOMOTO KK (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-20030057406-A1 | Resin additive composition and process for producing the same | AJINOMOTO CO., INC. (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1253168-A1 | RESIN ADDITIVE COMPOSITION AND PROCESS FOR PRODUCING THE SAME | Ajinomoto Co., Inc. (JP) | 2002-10-30 | — | — | EP | disclosed |
| US-4440888-A | Fire resistant hot-melt adhesives containing modified polyethylene | EASTMAN KODAK COMPANY (US) | 1984-04-03 | — | — | US | disclosed |