SCHEMBL3420702

SCHEMBL3420702

Cc1cc(S(=O)(=O)O)c(N)cc1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.39
TP53 P04637 1/20 0.39
CREBBP Q92793 1/20 0.39
CYP1A2 P05177 1/20 0.38
ALDH1A1 P00352 6/20 0.36
HSD17B10 Q99714 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
TTR P02766 1/20 0.35
NQO1 P15559 1/20 0.35
SUMO2 P61956 2/20 0.35
SUMO1 P63165 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
SENP2 Q9HC62 2/20 0.35
SENP1 Q9P0U3 2/20 0.35
SENP3 Q9H4L4 1/20 0.35
KDM4E B2RXH2 3/20 0.34
CASP6 P55212 2/20 0.34
GAA P10253 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6938187 0.84 CYP3A4 (0.44) BRD4TP53CREBBPCYP1A2ALDH1A1
SCHEMBL3419086 0.84 ALDH1A1 (0.40) BRD4TP53CREBBPCYP1A2ALDH1A1
SCHEMBL31697699 0.82 BRD4 (0.49) BRD4TP53CREBBPALDH1A1HSD17B10
SCHEMBL428347 0.82 CYP3A4 (0.42) BRD4TP53CREBBPCYP1A2ALDH1A1
SCHEMBL1755030 0.82 BRD4 (0.49) BRD4TP53CREBBPALDH1A1HSD17B10
SCHEMBL3422621 0.82 ALDH1A1 (0.39) BRD4TP53CREBBPCYP1A2ALDH1A1
SCHEMBL7032447 0.78 CYP3A4 (0.48) BRD4TP53CREBBPCYP1A2ALDH1A1
SCHEMBL1755154 0.78 BRD4 (0.49) BRD4TP53CREBBPCYP1A2ALDH1A1
SCHEMBL72936 0.77 CD44 (0.54) BRD4TP53CREBBPALDH1A1HSD17B10
SCHEMBL29489238 0.77 CD44 (0.54) BRD4TP53CREBBPALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010057830-A1 RING FLUORINATED REACTIVE DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2010-05-27 WO disclosed