Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL3420867 | 0.93 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1TSHR | |
| Cyclohexanone SCHEMBL5010011 | 0.85 | TRIM24 (0.61) | TRIM24TRIM33ALDH1A1 | |
| Ethylene SCHEMBL65177 | 0.82 | TRIM24 (0.54) | TRIM24TRIM33ALDH1A1TSHR | |
| Ethylene SCHEMBL28491509 | 0.82 | TRIM24 (0.54) | TRIM24TRIM33ALDH1A1TSHR | |
| Ethylene Glycol SCHEMBL7680716 | 0.81 | GABRP (0.31) | TRIM24TRIM33 | |
| Cyclopentanone SCHEMBL28250684 | 0.80 | TRIM24 (0.67) | TRIM24TRIM33ALDH1A1TSHR | |
| Ethylene SCHEMBL1001063 | 0.78 | — | — | |
| Cyclohexanone SCHEMBL5010013 | 0.78 | TRIM24 (0.69) | TRIM24TRIM33ALDH1A1TSHR | |
| Cycloheptanone SCHEMBL28843909 | 0.78 | TRIM24 (0.69) | TRIM24TRIM33ALDH1A1TSHR | |
| Cyclohexanone SCHEMBL28351148 | 0.78 | TRIM24 (0.69) | TRIM24TRIM33ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232138-B | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-112812782-B | Cyclohexane benzoxazole liquid crystal compound, preparation method and application thereof | 西安瑞联新材料股份有限公司 | 2023-09-29 | — | — | CN | claimed |
| WO-2023178826-A1 | COPPER PLATING ADDITIVE, COPPER PLATING SOLUTION AND USE THEREOF | 江阴纳力新材料科技有限公司 | 2023-09-28 | — | — | WO | claimed |
| WO-2023178825-A1 | COPPER BRUSH PLATING PROCESS FOR PLASTIC FILM | 江阴纳力新材料科技有限公司 | 2023-09-28 | — | — | WO | claimed |
| CN-114835623-B | New method for synthesizing Almond alkaloid (+/-) membrane | 河北桑迪亚医药技术有限责任公司 | 2023-07-04 | — | — | CN | claimed |
| CN-116178304-A | Synthesis method of pramipexole dihydrochloride | 中国药科大学 | 2023-05-30 | — | — | CN | claimed |
| CN-115894181-A | Synthetic method of cyclohexenyl cyclohexyl difluorobenzene liquid crystal compound | 渭南高新区海泰新型电子材料有限责任公司 | 2023-04-04 | — | — | CN | claimed |
| CN-114561674-B | Plastic film brush copper plating process | 江阴纳力新材料科技有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-114540889-B | Copper plating additive, copper plating solution and application thereof | 江阴纳力新材料科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-113881442-B | Liquid crystal compound containing polyfluornonaphthalene and preparation method thereof | 宁夏中星显示材料有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115636724-A | 4-fluoro-4-methylcyclohexanol and preparation method thereof | 浙大宁波理工学院 | 2023-01-24 | — | — | CN | claimed |
| CN-115232138-A | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2022-10-25 | — | — | CN | claimed |
| CN-114835623-A | New method for synthesizing Tetragoniaceae alkaloid (+/-) Mesembrine | 河北桑迪亚医药技术有限责任公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114561674-A | Plastic film brush copper plating process | 江阴纳力新材料科技有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-114540889-A | Copper plating additive, copper plating solution and application thereof | 江阴纳力新材料科技有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-113881442-A | Liquid crystal compound containing polyfluornonaphthalene and preparation method thereof | 宁夏中星显示材料有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-111763193-B | Synthesis method of 1, 4-cyclohexanedione monoethylene glycol ketal | 河北美星化工有限公司 | 2021-08-03 | — | — | CN | claimed |
| CN-109503545-B | Preparation method of 1, 4-cyclohexanedione monoethylene glycol ketal | 彩客化学(沧州)有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-111763193-A | Synthesis method of 1, 4-cyclohexanedione monoethylene glycol ketal | 河北美星化工有限公司 | 2020-10-13 | — | — | CN | claimed |
| CN-118340916-A | Near infrared fluorescent dye and application thereof in fluorescence guided surgery | 华东理工大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-118026797-A | Preparation method of negative liquid crystal monomer | 西安瑞联新材料股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2024061118-A1 | MACROCYCLIC NITROGEN-CONTAINING CROWN ETHER COMPOUND AND USE THEREOF AS PROTEIN KINASE INHIBITOR | 科辉智药生物科技（无锡）有限公司 | 2024-03-28 | — | — | WO | disclosed |
| CN-117658973-A | Infrared fluorescent dye and application thereof | 华东理工大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-117645533-A | Synthesis method of 4- (trifluoromethyl) cyclohexanone | 泰州精英化成医药科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-115232138-B | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115232138-B | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-117379319-A | Root canal sealing drug PEG-based temperature-sensitive hydrogel preparation and preparation method thereof | 天津医科大学口腔医院 | 2024-01-12 | — | — | CN | disclosed |
| CN-116981670-A | Polycyclic compound containing nitrogen heterocycle, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-112812782-B | Cyclohexane benzoxazole liquid crystal compound, preparation method and application thereof | 西安瑞联新材料股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023178826-A1 | COPPER PLATING ADDITIVE, COPPER PLATING SOLUTION AND USE THEREOF | 江阴纳力新材料科技有限公司 | 2023-09-28 | — | — | WO | disclosed |
| WO-2023178825-A1 | COPPER BRUSH PLATING PROCESS FOR PLASTIC FILM | 江阴纳力新材料科技有限公司 | 2023-09-28 | — | — | WO | disclosed |
| CN-114835623-B | New method for synthesizing Almond alkaloid (+/-) membrane | 河北桑迪亚医药技术有限责任公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116348470-A | Method for producing octahydrothienoquinoline compound and intermediate therefor | 橘生药品工业株式会社 | 2023-06-27 | — | — | CN | disclosed |
| CN-116348470-A | Method for producing octahydrothienoquinoline compound and intermediate therefor | 橘生药品工业株式会社 | 2023-06-27 | — | — | CN | disclosed |
| CN-115215832-B | Preparation method of 1,4-cyclohexanedione mono ketal | 无锡科华生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116178304-A | Synthesis method of pramipexole dihydrochloride | 中国药科大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-116178304-A | Synthesis method of pramipexole dihydrochloride | 中国药科大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-115894181-A | Synthetic method of cyclohexenyl cyclohexyl difluorobenzene liquid crystal compound | 渭南高新区海泰新型电子材料有限责任公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115894181-A | Synthetic method of cyclohexenyl cyclohexyl difluorobenzene liquid crystal compound | 渭南高新区海泰新型电子材料有限责任公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114561674-B | Plastic film brush copper plating process | 江阴纳力新材料科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114561674-B | Plastic film brush copper plating process | 江阴纳力新材料科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114540889-B | Copper plating additive, copper plating solution and application thereof | 江阴纳力新材料科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-114540889-B | Copper plating additive, copper plating solution and application thereof | 江阴纳力新材料科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-113881442-B | Liquid crystal compound containing polyfluornonaphthalene and preparation method thereof | 宁夏中星显示材料有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113881442-B | Liquid crystal compound containing polyfluornonaphthalene and preparation method thereof | 宁夏中星显示材料有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115636724-A | 4-fluoro-4-methylcyclohexanol and preparation method thereof | 浙大宁波理工学院 | 2023-01-24 | — | — | CN | disclosed |
| CN-115636724-A | 4-fluoro-4-methylcyclohexanol and preparation method thereof | 浙大宁波理工学院 | 2023-01-24 | — | — | CN | disclosed |
| CN-115246833-A | Preparation method of olatinib compound and intermediate compound thereof | 洛阳惠中兽药有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115232138-A | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232138-A | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115215832-A | Preparation method of 1,4-cyclohexanedione mono-ketal | 无锡科华生物科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-111741946-B | Indoleamine 2, 3-dioxygenase inhibitors and their use in medicine | 厦门宝太生物科技股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114835623-A | New method for synthesizing Tetragoniaceae alkaloid (+/-) Mesembrine | 河北桑迪亚医药技术有限责任公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114835623-A | New method for synthesizing Tetragoniaceae alkaloid (+/-) Mesembrine | 河北桑迪亚医药技术有限责任公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114716449-A | Preparation method of 2-methoxy-6-ethylene ketal-5, 7, 8-trihydroquinoline | 浙江工业大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114561674-A | Plastic film brush copper plating process | 江阴纳力新材料科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-114540889-A | Copper plating additive, copper plating solution and application thereof | 江阴纳力新材料科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540889-A | Copper plating additive, copper plating solution and application thereof | 江阴纳力新材料科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114213327-A | Synthesis method of (-) -huperzine A | 杭州易合生物医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-113881442-A | Liquid crystal compound containing polyfluornonaphthalene and preparation method thereof | 宁夏中星显示材料有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-107365312-B | Novel method for preparing Octacitinib | 瑞博(杭州)医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-111471010-B | Indoleamine-2, 3-dioxygenase (IDO) inhibitors | 杭州阿诺生物医药科技有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-214233991-U | Preparation facilities of 1-methoxy-4-oxygen-cyclohexanecarboxylic acid methyl ester | 苏利制药科技江阴有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-111763193-B | Synthesis method of 1, 4-cyclohexanedione monoethylene glycol ketal | 河北美星化工有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-111763193-B | Synthesis method of 1, 4-cyclohexanedione monoethylene glycol ketal | 河北美星化工有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-111763193-B | Synthesis method of 1, 4-cyclohexanedione monoethylene glycol ketal | 河北美星化工有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-213761865-U | Multifunctional biological safety cabinet for producing 1, 4-cyclohexanedione monoethylene ketal | 石家庄久睿科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-111471011-B | Preparation method of high-activity indoleamine 2, 3-dioxygenase inhibitor | 杭州阿诺生物医药科技有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-107827721-B | Method for synthesizing 4-fluorocyclohexanone | 上海恩氟佳科技有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2021043209-A1 | RET INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 广东东阳光药业有限公司 | 2021-03-11 | — | — | WO | disclosed |
| CN-111471035-B | Preparation method of IDO inhibitor | 杭州阿诺生物医药科技有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112166379-A | Resist underlayer film forming composition using cyclic carbonyl compound | 日产化学株式会社 | 2021-01-01 | — | — | CN | disclosed |
| CN-107522600-B | Ethylene oxide group-containing compound, composition and application thereof | 江苏和成显示科技有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-109503545-B | Preparation method of 1, 4-cyclohexanedione monoethylene glycol ketal | 彩客化学(沧州)有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-109503545-B | Preparation method of 1, 4-cyclohexanedione monoethylene glycol ketal | 彩客化学(沧州)有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111763193-A | Synthesis method of 1, 4-cyclohexanedione monoethylene glycol ketal | 河北美星化工有限公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-111763193-A | Synthesis method of 1, 4-cyclohexanedione monoethylene glycol ketal | 河北美星化工有限公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-111763193-A | Synthesis method of 1, 4-cyclohexanedione monoethylene glycol ketal | 河北美星化工有限公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-111741946-A | Indoleamine 2, 3-dioxygenase inhibitors and their use in medicine | 杭州阿诺生物医药科技有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-111712490-A | Amino-substituted pyridone derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111574442-A | Preparation method of indoleamine 2, 3-dioxygenase inhibitor | 杭州阿诺生物医药科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-107573212-B | Synthesis method of trans-4-alkyl cyclohexyl benzene structure liquid crystal intermediate and monomer | 宁夏中星显示材料有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111471010-A | Indoleamine-2, 3-dioxygenase (IDO) inhibitors | 杭州阿诺生物医药科技有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-111471011-A | Preparation method of high-activity indoleamine 2, 3-dioxygenase inhibitor | 杭州阿诺生物医药科技有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-111471035-A | Preparation method of IDO inhibitor | 杭州阿诺生物医药科技有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-109181711-B | Negative liquid crystal compound and preparation method thereof | 河北迈尔斯通电子材料有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111039917-A | Preparation method of 1, 4-cyclohexanedione mono-ketal | 彩客化学(沧州)有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-105817228-B | The method for directly preparing cyclohexanone glycol ketal compounds using flyash catalysis | 黄山学院 | 2018-11-23 | — | — | CN | disclosed |
| CN-104829628-B | Octahydro thieno quinoline, the pharmaceutical composition comprising the derivative and their purposes | 橘生药品工业株式会社 | 2018-01-09 | — | — | CN | disclosed |
| CN-102803333-B | Epoxy resin composition, prepreg and cured products thereof | NIPPON KAYAKU KK | 2015-04-29 | — | — | CN | disclosed |
| CN-102643276-B | Immunosuppressive agent FR901483 intermediate and synthetic method thereof | UNIV LANZHOU | 2015-02-18 | — | — | CN | disclosed |
| US-8846946-B2 | Germinal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2014-09-30 | — | — | US | disclosed |
| US-20140213795-A1 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| CN-101952281-B | Indole and indazole derivatives having a cell-, tissue- and organ-preserving effect | LG LIFE SCIENCES LTD | 2014-04-02 | — | — | CN | disclosed |
| US-8389443-B2 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| CN-102822148-A | Therapeutic agent or prophylactic agent for fibromyalgia | TORAY INDUSTRIES | 2012-12-12 | — | — | CN | disclosed |
| CN-102812008-A | Therapeutic agent or preventive agent for urine collection disorder | TORAY INDUSTRIES | 2012-12-05 | — | — | CN | disclosed |
| CN-101952281-A | Indole and indazole derivatives having a cell-, tissue- and organ-preserving effect | LG LIFE SCIENCES LTD | 2011-01-19 | — | — | CN | disclosed |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
| CN-101553231-A | Modulators of muscarinic receptors | VERTEX PHARMA (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-1438996-A | Bicyclic cyclohexylamines and their use NMDA receptor antogonists | WARNER LAMBERT CO (US) | 2003-08-27 | — | — | CN | disclosed |
| CN-1213306-A | Novel substituted imidazolium compounds | SMITHKLINE BEECHAM CORP (US) | 1999-04-07 | — | — | CN | disclosed |
| CN-1111671-A | Liquid crystal compound and liquid crystal combinated material | CHISSO CORP (JP) | 1995-11-15 | — | — | CN | disclosed |
| US-5426111-A | Antiallergens, antiinflammatory agent | ABBOTT LABORATORIES (US) | 1995-06-20 | — | — | US | disclosed |
| US-5407959-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1995-04-18 | — | — | US | disclosed |
| WO-1994005638-A1 | TRANS 1,4-DIETHER CYCLOHEXANE INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |
| WO-1994005638-A1 | TRANS 1,4-DIETHER CYCLOHEXANE INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213795-A1 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES | AGXT, GMNN, GLRX3 | TRIM24 4398/4885TRIM33 3717/4885ALDH1A1 3862/4885 |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | GMNN, AGXT, GEMIN5 | TRIM24 3517/4885TRIM33 2945/4885ALDH1A1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.