Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 12/20 | 0.64 |
| ▸ | CA1 | P00915 | 12/20 | 0.64 |
| ▸ | CA2 | P00918 | 12/20 | 0.64 |
| ▸ | CA9 | Q16790 | 12/20 | 0.64 |
| ▸ | CA4 | P22748 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473383 | 0.89 | CA1 (0.53) | CA12CA1CA2CA9CA4 | |
| SCHEMBL13111190 | 0.89 | CA1 (0.53) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3422237 | 0.88 | GFER (0.53) | CA12CA1CA2CA9CA4 | |
| SCHEMBL1135223 | 0.88 | CA1 (0.57) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3473546 | 0.88 | CA1 (0.52) | CA12CA1CA2CA9CA4 | |
| SCHEMBL13429353 | 0.88 | CA1 (0.60) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3423034 | 0.88 | CA1 (0.64) | CA12CA1CA2CA9CA4 | |
| SCHEMBL13637114 | 0.88 | CA1 (0.52) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3474408 | 0.88 | CA1 (0.52) | CA12CA1CA2CA9CA4 | |
| SCHEMBL597124 | 0.87 | CA1 (0.61) | CA12CA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045505-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045505-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2010-04-22 | — | — | WO | disclosed |