Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.60 |
| ▸ | CA2 | P00918 | 12/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 10/20 | 0.52 |
| ▸ | CA4 | P22748 | 6/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.48 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473546 | 0.90 | CA1 (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3474408 | 0.90 | CA1 (0.52) | CA1CA2LMNACA12CA9 | |
| SCHEMBL13111190 | 0.89 | CA1 (0.53) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3473383 | 0.89 | CA1 (0.53) | CA1CA2CA12CA9CA4 | |
| SCHEMBL12317640 | 0.88 | LMNA (0.56) | CA1CA2LMNAALDH1A1THRB | |
| SCHEMBL13637114 | 0.88 | CA1 (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1135223 | 0.88 | CA1 (0.57) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3423034 | 0.88 | CA1 (0.64) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3421164 | 0.88 | CA12 (0.64) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL597124 | 0.87 | CA1 (0.61) | CA1CA2CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045505-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2010-04-22 | — | — | WO | disclosed |