Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261205 | 0.85 | MEN1 (0.49) | MEN1GAAKMT2APCSK9CA2 | |
| SCHEMBL1260956 | 0.85 | MEN1 (0.49) | MEN1GAAKMT2APCSK9CA2 | |
| SCHEMBL19765482 | 0.85 | MEN1 (0.45) | MEN1GAAKMT2APCSK9CA2 | |
| SCHEMBL1260951 | 0.85 | MEN1 (0.49) | MEN1GAAKMT2APCSK9CA2 | |
| SCHEMBL3423364 | 0.83 | CYP2D6 (0.43) | MEN1GAAKMT2APCSK9CA2 | |
| SCHEMBL25324125 | 0.83 | MEN1 (0.43) | MEN1GAAKMT2APCSK9CA2 | |
| SCHEMBL17788024 | 0.83 | MEN1 (0.43) | MEN1GAAKMT2APCSK9CA2 | |
| SCHEMBL25921359 | 0.83 | MEN1 (0.43) | MEN1GAAKMT2APCSK9CA2 | |
| SCHEMBL26093592 | 0.83 | MEN1 (0.43) | MEN1GAAKMT2ACA2CA12 | |
| SCHEMBL3422488 | 0.83 | MEN1 (0.43) | MEN1GAAKMT2APCSK9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065709-A2 | HYDROXAMIC ACID DERIVATIVES, PREPARATION AND THERAPEUTIC USES THEREOF | KHAN AMIN (US) | 2010-06-10 | — | — | WO | disclosed |