⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451003 | 1.00 | — | — | |
| SCHEMBL16181947 | 0.85 | SLC7A5 (0.50) | — | |
| SCHEMBL6684752 | 0.81 | SLC7A5 (0.57) | — | |
| SCHEMBL2313042 | 0.79 | SLC7A5 (0.55) | — | |
| SCHEMBL16300972 | 0.77 | — | — | |
| SCHEMBL16490238 | 0.77 | — | — | |
| Valine SCHEMBL9321177 | 0.76 | SLC7A5 (0.83) | — | |
| Valine SCHEMBL628974 | 0.75 | SLC7A5 (0.94) | — | |
| Valine SCHEMBL135483 | 0.75 | — | — | |
| Valine SCHEMBL4078935 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097407-A1 | MODIFIED AMATOXINS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-06-08 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-9603943-B2 | Polyesteramide platform for site specific drug delivery | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-9603943-B2 | Polyesteramide platform for site specific drug delivery | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150290336-A1 | POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-10-15 | — | — | US | disclosed |
| US-9095619-B2 | Polyesteramide platform for site specific drug delivery | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2015-08-04 | — | — | US | disclosed |
| EP-2450194-B1 | Recording medium | CANON KK (JP) | 2015-06-17 | — | — | EP | disclosed |
| US-20150010491-A1 | POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-01-08 | — | — | US | disclosed |
| US-8865148-B2 | Polyesteramide platform for site specific drug delivery | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-10-21 | — | — | US | disclosed |
| US-8722159-B2 | Recording medium | CANON KABUSHIKI KAISHA (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8658210-B2 | Polyesteramide platform for site specific drug delivery | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| CN-102336083-B | Recording medium | CANON KK | 2014-01-22 | — | — | CN | disclosed |
| EP-2450194-A2 | Recording medium | Canon Kabushiki Kaisha (JP) | 2012-05-09 | — | — | EP | disclosed |
| US-20120015119-A1 | RECORDING MEDIUM | CANON KABUSHIKI KAISHA (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20070243256-A1 | Polyesteramide platform for site specific drug delivery | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2007-10-18 | — | — | US | disclosed |
| EP-0595163-B1 | Process for producing L-isoleucine | KYOWA HAKKO KOGYO KK (JP) | 1998-06-24 | — | — | EP | disclosed |
| EP-0131171-B1 | CORYNEFORM BACTERIA CARRYING RECOMBINANT PLASMIDS AND THEIR USE IN THE FERMENTATIVE PRODUCTION OF L-THREONINE AND L-ISOLEUCINE | AJINOMOTO CO., INC. (JP) | 1987-10-21 | — | — | EP | disclosed |
| US-4601983-A | Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-threonine and L-isoleucine | AJINOMOTO CO., INC. (JP) | 1986-07-22 | — | — | US | disclosed |
| EP-0131171-A1 | Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of l-threonine and l-isoleucine | AJINOMOTO CO., INC. (JP) | 1985-01-16 | — | — | EP | disclosed |
| US-3959075-A | CULTURING CORYNEFORM MUTANT | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-05-25 | — | — | US | disclosed |