Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313042 | 0.92 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL342124 | 0.81 | — | — | |
| SCHEMBL2451003 | 0.81 | — | — | |
| SCHEMBL16490238 | 0.79 | — | — | |
| SCHEMBL16300972 | 0.79 | — | — | |
| Valine SCHEMBL23777447 | 0.77 | SLC7A5 (0.94) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL9439900 | 0.77 | SLC7A5 (0.94) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL10775583 | 0.77 | SLC7A5 (0.94) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL3402665 | 0.77 | SLC7A5 (0.94) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Hydrochloric Acid SCHEMBL7200248 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852502-B1 | LANTIBIOTIC MUTANTS AND CHIMERAS OF ENHANCED STABILITY AND ACTIVITY | UNIV MARYLAND (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6153405-A | NUCLEIC ACID WHICH ENCODES A LEADER SEQUENCE FROM NISIN AND/OR SUBTILIN AND A LANTIBIOTIC; FOR RECOMBINANT PRODUCTION OF ANTIBIOTICS | THE UNIVERSITY OF MARYLAND (US) | 2000-11-28 | — | — | US | disclosed |
| US-5861275-A | GENE-ENCODED ANTIMICROBIAL PEPTIDES; POLYNUCLEIC ACIDS WHICH ENCODE A CHIMERIC OR MUTANT LANTIBIOTIC | THE UNIVERSITY OF MARYLAND (US) | 1999-01-19 | — | — | US | disclosed |