Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10321703 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL16353929 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL10321597 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL27112153 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL16353859 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL10321022 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL139351 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL16353930 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL10320909 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19NR4A1MAOATOP2A | |
| SCHEMBL832504 | 0.98 | CYP1A2 (0.53) | CYP1A2CYP2C19NR4A1MAOATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9095623-B2 | Terminally-functionalized conjugates and uses thereof | SMARTCELLS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-9095623-B2 | Terminally-functionalized conjugates and uses thereof | SMARTCELLS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140121159-A1 | TERMINALLY–FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2014-05-01 | — | — | US | disclosed |
| US-20140121159-A1 | TERMINALLY–FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2014-05-01 | — | — | US | disclosed |
| US-8623345-B2 | Terminally-functionalized conjugates and uses thereof | Smartcells (US) | 2014-01-07 | — | — | US | disclosed |
| US-8623345-B2 | Terminally-functionalized conjugates and uses thereof | Smartcells (US) | 2014-01-07 | — | — | US | disclosed |
| US-8268908-B2 | Pigment dispersion liquid, inkjet recording ink, inkjet recording method, ink cartridge and inkjet recording apparatus | CANON FINETECH INC. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20120014908-A1 | TERMINALLY-FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. | 2012-01-19 | — | — | US | disclosed |
| US-20120014908-A1 | TERMINALLY-FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. | 2012-01-19 | — | — | US | disclosed |
| US-7825199-B1 | mediated by transition metal complex in redox reaction of atom transfer Atom Transfer Coupling Reaction to/from initiator or dormant polymer and growing active polymer chain ends; transition metal held in close conjunction with a solid support; salt containing a soluble organic counterion; styrene graft | CARNEGIE MELLON UNIVERSITY (US) | 2010-11-02 | — | — | US | disclosed |
| WO-2010107519-A1 | TERMINALLY-FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20100021635-A1 | PIGMENT DISPERSION LIQUID, INKJET RECORDING INK, INKJET RECORDING METHOD, INK CARTRIDGE AND INKJET RECORDING APPARATUS | CANON FINETECH INC. (JP) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121159-A1 | TERMINALLY–FUNCTIONALIZED CONJUGATES AND USES THEREOF | NPY1R, NTSR1, GRPR | CYP1A2 2345/4885CYP2C19 1668/4885NR4A1 1622/4885 |
| US-20120014908-A1 | TERMINALLY-FUNCTIONALIZED CONJUGATES AND USES THEREOF | NPY1R, NTSR1, GRPR | CYP1A2 2107/4885CYP2C19 1490/4885NR4A1 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.