Maxacalcitol

Maxacalcitol

SCHEMBL342279

C=C1C(=CC=C2CCC[C@@]3(C)C2CC[C@@H]3[C@H](C)OCCC(C)(C)O)C[C@@H](O)C[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VDR P11473 13/20 1.00
MAPT P10636 2/20 0.79
ADORA3 P0DMS8 2/20 0.79
SLC6A2 P23975 2/20 0.79
AGTR1 P30556 2/20 0.79
NR1I2 O75469 1/20 0.79
ABCB11 O95342 1/20 0.79
GC P02774 1/20 0.79
PGR P06401 1/20 0.79
RXRA P19793 1/20 0.79
CHRM3 P20309 1/20 0.79
CNR1 P21554 1/20 0.79
HTR2C P28335 1/20 0.79
MAPK1 P28482 1/20 0.79
SLC6A4 P31645 1/20 0.79
ADRA1A P35348 1/20 0.79
PTGS2 P35354 1/20 0.79
OPRD1 P41143 1/20 0.79
OPRK1 P41145 1/20 0.79
SLC6A3 Q01959 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maxacalcitol SCHEMBL5617040 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL14490724 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL5153677 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL25095406 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL17975926 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL24066887 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL4893368 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL20461177 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL7203090 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1
Maxacalcitol SCHEMBL3189866 1.00 VDR (1.00) VDRMAPTADORA3SLC6A2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 701 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111447-A1 TREATMENT OF CANCER WITH DRUG COMBINATIONS FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (US) 2025-05-30 WO claimed
US-20240374734-A1 Immunomodulatory Combinations of Antigen and Drug-Lipid Conjugate INTEGRATED NANOTHERAPEUTICS INC. (CA) 2024-11-14 US claimed
EP-4398930-A1 IMMUNOMODULATORY COMBINATIONS OF ANTIGEN AND DRUG-LIPID CONJUGATE Integrated Nanotherapeutics Inc. (CA) 2024-07-17 EP claimed
CN-118215496-A Immunomodulatory combinations of antigens and drug-lipid conjugates 集成纳米治疗股份有限公司 2024-06-18 CN claimed
US-20230398130-A1 METHODS AND COMPOSITIONS FOR DIFFERENTIATING STEM CELLS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-12-14 US claimed
EP-4232012-A1 METHODS AND COMPOSITIONS FOR DIFFERENTIATING STEM CELLS Massachusetts Institute of Technology (US) 2023-08-30 EP claimed
EP-3112476-B1 METHODS, COMPOSITIONS, USES, AND KITS USEFUL FOR VITAMIN D DEFICIENCY AND RELATED DISORDERS EIRGEN PHARMA LTD (IE) 2023-08-02 EP claimed
WO-2023035068-A1 IMMUNOMODULATORY COMBINATIONS OF ANTIGEN AND DRUG-LIPID CONJUGATE INTEGRATED NANOTHERAPEUTICS INC. (CA) 2023-03-16 WO claimed
WO-2022087526-A1 METHODS AND COMPOSITIONS FOR DIFFERENTIATING STEM CELLS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-04-28 WO claimed
CN-110612119-A Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents 西雅图儿童医院(DBA西雅图儿童研究所) 2019-12-24 CN claimed
US-6248732-B1 ADMINISTERING MIXTURE OF ACTIVATED VITAMIN D AND VITAMIN C TO EYE TO TREAT POST OPHTHALMIC SURGERY TISSUE DETERIORATION KATSUHIKO MUKAI (JP) 2001-06-19 US claimed
US-6187331-B1 Composition for prophylaxis and/or treatment of dry syndrome comprising vitamin D NEW VISION CO., LTD. (JP) 2001-02-13 US claimed
EP-1059085-A1 LANGERHANS CELL MIGRATION INHIBITORS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-12-13 EP claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061604-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061541-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
EP-0998925-A1 MEDICINAL COMPOSITIONS FOR TOPICAL ADMINISTRATION CONTAINING VITAMIN D AND VITAMIN K New Vision Co., Ltd. (JP) 2000-05-10 EP claimed
EP-0992242-A1 VITAMIN D-CONTAINING PREVENTIVES AND/OR REMEDIES FOR CONJUNCTIVAL/CORNEAL XEROSIS New Vision Co., Ltd. (JP) 2000-04-12 EP claimed
US-5876709-A Ophthalmic composition containing active Vitamin D NEW VISION CO., LTD. (JP) 1999-03-02 US claimed
EP-0815862-A1 OPHTHALMOLOGICAL COMPOSITION COMPRISING ACTIVATED VITAMIN D Mukai, Katsuhiko (JP) 1998-01-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374734-A1 Immunomodulatory Combinations of Antigen and Drug-Lipid Conjugate LY96, CD74, TLR9 VDR 671/4885MAPT 3671/4885ADORA3 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.