Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MECP2 | P51608 | 1/20 | 0.89 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 13/20 | 0.61 |
| ▸ | RAB9A | P51151 | 12/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29813232 | 1.00 | MECP2 (0.89) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL653811 | 0.94 | MECP2 (1.00) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1142913 | 0.92 | MECP2 (0.83) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11508555 | 0.92 | MECP2 (0.83) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL653790 | 0.89 | NPC1 (0.72) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3910760 | 0.87 | MECP2 (0.69) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2835027 | 0.87 | MECP2 (0.69) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2214351 | 0.87 | MECP2 (0.69) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29454527 | 0.86 | MECP2 (0.68) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1543902 | 0.85 | MECP2 (0.67) | MECP2ATAD2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | claimed |
| WO-2007149395-A2 | 2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | AMPHORA DISCOVERY CORPORATION (US) | 2007-12-27 | — | — | WO | claimed |
| US-4526835-A | Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure | HITACHI, LTD. (JP) | 1985-07-02 | — | — | US | claimed |
| US-4486583-A | MOLDING MATERIALS, COATINGS | HITACHI, LTD. (JP) | 1984-12-04 | — | — | US | claimed |
| US-4393188-A | PRINTED CIRCUITS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1983-07-12 | — | — | US | claimed |
| US-4390596-A | POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER | RHONE-POULENC INDUSTRIES (FR) | 1983-06-28 | — | — | US | claimed |
| US-4283522-A | BY HEATING WITH A DIAMINE | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1981-08-11 | — | — | US | claimed |
| US-4238591-A | BIS-MALEIMIDE, SILANEDIOL OR SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1980-12-09 | — | — | US | claimed |
| US-11965060-B2 | Fluorine-containing epoxy resin for electrical materials and method for manufacturing same | DAIKIN INDUSTRIES, LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| US-20220298294-A1 | COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT | DAIKIN INDUSTRIES, LTD. (JP) | 2022-09-22 | — | — | US | disclosed |
| EP-4053214-A1 | COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT | Daikin Industries, Ltd. (JP) | 2022-09-07 | — | — | EP | disclosed |
| US-20220219127-A1 | POLY(IMIDE-OXADIAZOLE) MEMBRANES FOR GAS SEPARATION APPLICATIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2022-07-14 | — | — | US | disclosed |
| US-20220081507-A1 | FLUORINE-CONTAINING EPOXY RESIN FOR ELECTRICAL MATERIALS AND METHOD FOR MANUFACTURING SAME | DAIKIN INDUSTRIES, LTD. (JP) | 2022-03-17 | — | — | US | disclosed |
| EP-3960788-A1 | FLUORINE-CONTAINING EPOXY RESIN FOR ELECTRICAL MATERIALS AND METHOD FOR MANUFACTURING SAME | DAIKIN INDUSTRIES, LTD. (JP) | 2022-03-02 | — | — | EP | disclosed |
| US-4010220-A | AMINO COMPOUND, POLYURETHANE ELASTOMER | RHONE-POULENC INDUSTRIES (FR) | 1977-03-01 | — | — | US | disclosed |
| US-4005154-A | Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups | RHONE-POULENC S.A. (FR) | 1977-01-25 | — | — | US | disclosed |
| US-3998904-A | POLYAMINES WITH IMIDE GROUPS | RHONE-POULENC S.A. (FR) | 1976-12-21 | — | — | US | disclosed |
| US-3970714-A | Heat-stable polyimide resin modified by unsaturated polyester | RHONE-POULENC S.A. (FR) | 1976-07-20 | — | — | US | disclosed |
| US-3966678-A | Maleic anhydride-polyaldimine prepolymers | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3933745-A | Imide copolymers possessing hydroxyl groups | RHONE-POULENC S.A. (FR) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | ATP5ME, ATP5MG, ATP5MK | MECP2 4377/4885ATAD2 531/4885NPC1 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.