Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931203 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL17700509 | 0.88 | HTT (0.55) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL28786089 | 0.87 | LCK (0.73) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL12444067 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHTTLCK | |
| SCHEMBL19667102 | 0.85 | LCK (0.65) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL18713914 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL7349901 | 0.85 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL18700941 | 0.84 | HTT (0.55) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL31166907 | 0.84 | CYP3A4 (0.50) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL7348461 | 0.84 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014203132-A1 | SUBSTITUTED BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014203132-A1 | SUBSTITUTED BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |
| US-7759459-B2 | Fluorescent assays for protein kinases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-07-20 | — | — | US | disclosed |
| US-7759459-B2 | Fluorescent assays for protein kinases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-07-20 | — | — | US | disclosed |
| US-7759459-B2 | Fluorescent assays for protein kinases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-07-20 | — | — | US | disclosed |
| US-20050054024-A1 | Fluorescent assays for protein kinases | NATIONAL INSTITUTES OF HEALTH | 2005-03-10 | — | — | US | disclosed |
| WO-2004062475-A2 | FLUORESCENT ASSAYS FOR PROTEIN KINASES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2004-07-29 | — | — | WO | disclosed |