⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284709 | 0.84 | — | — | |
| SCHEMBL3059429 | 0.84 | — | — | |
| SCHEMBL11010950 | 0.83 | — | — | |
| Fluoride SCHEMBL27138066 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL17156481 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6263417 | 0.81 | — | — | |
| SCHEMBL28803333 | 0.81 | ALDH1A1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL29010691 | 0.81 | — | — | |
| SCHEMBL10364048 | 0.79 | PLA2G1B (0.52) | — | |
| SCHEMBL10362344 | 0.79 | PLA2G1B (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112618728-B | Dual-response prodrug containing polysialic acid group, synthetic method thereof and application thereof in pharmaceutical preparation | 绍兴文理学院 | 2022-07-29 | — | — | CN | claimed |
| CN-112618728-A | Dual-response prodrug containing polysialic acid group, synthetic method thereof and application thereof in pharmaceutical preparation | 绍兴文理学院 | 2021-04-09 | — | — | CN | claimed |
| EP-2665744-B1 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIV ROCHESTER (US) | 2015-04-08 | — | — | EP | claimed |
| US-8986953-B2 | Macrocyclic compounds with a hybrid peptidic/non-peptidic backbone and methods for their preparation | UNIVERSITY OF ROCHESTER (US) | 2015-03-24 | — | — | US | claimed |
| US-20130330773-A1 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | NATIONAL SCIENCE FOUNDATION | 2013-12-12 | — | — | US | claimed |
| EP-2665744-A2 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF ROCHESTER (US) | 2013-11-27 | — | — | EP | claimed |
| WO-2012100176-A2 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF ROCHESTER (US) | 2012-07-26 | — | — | WO | claimed |
| EP-4447944-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES | THE PENN STATE RESEARCH FOUNDATION (US) | 2024-10-23 | — | — | EP | disclosed |
| US-20240335540-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES | PENN STATE RES FOUND (US) | 2024-10-10 | — | — | US | disclosed |
| CN-118613287-A | Compositions and methods for targeted delivery of therapeutic and/or diagnostic substances | 宾夕法尼亚州立大学研究基金会 | 2024-09-06 | — | — | CN | disclosed |
| WO-2023114466-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-06-22 | — | — | WO | disclosed |
| CN-112618728-B | Dual-response prodrug containing polysialic acid group, synthetic method thereof and application thereof in pharmaceutical preparation | 绍兴文理学院 | 2022-07-29 | — | — | CN | disclosed |
| CN-112618728-A | Dual-response prodrug containing polysialic acid group, synthetic method thereof and application thereof in pharmaceutical preparation | 绍兴文理学院 | 2021-04-09 | — | — | CN | disclosed |
| US-8986953-B2 | Macrocyclic compounds with a hybrid peptidic/non-peptidic backbone and methods for their preparation | UNIVERSITY OF ROCHESTER (US) | 2015-03-24 | — | — | US | disclosed |
| US-20130330773-A1 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | NATIONAL SCIENCE FOUNDATION | 2013-12-12 | — | — | US | disclosed |
| EP-2665744-A2 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF ROCHESTER (US) | 2013-11-27 | — | — | EP | disclosed |
| US-20120315388-A1 | BONDING SYSTEM COMPRISING AN ADHESIVE OR SEALANT AND A PRIMER | SIKA TECHNOLOGY AG (CH) | 2012-12-13 | — | — | US | disclosed |
| WO-2012100176-A2 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF ROCHESTER (US) | 2012-07-26 | — | — | WO | disclosed |
| US-20120012251-A1 | HOT CURING OR HEAT-ACTIVATED COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE | SIKA TECHNOLOGY AG (CH) | 2012-01-19 | — | — | US | disclosed |
| EP-0023707-A1 | Substituted tetraazatricyclic compounds, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |