Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 1/20 | 1.00 |
| ▸ | INSR | P06213 | 3/20 | 0.69 |
| ▸ | IGF1R | P08069 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.63 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424039 | 1.00 | PTP4A3 (1.00) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL30287682 | 1.00 | PTP4A3 (1.00) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL12990075 | 1.00 | PTP4A3 (1.00) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL623775 | 0.82 | IGF1R (1.00) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL622800 | 0.82 | PIK3CG (0.80) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL6090652 | 0.82 | IGF1R (0.74) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL6090645 | 0.82 | IGF1R (0.74) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL622799 | 0.82 | PIK3CG (0.80) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL623774 | 0.82 | IGF1R (1.00) | PTP4A3INSRIGF1RMEN1KMT2A | |
| SCHEMBL29910211 | 0.82 | IGF1R (0.74) | PTP4A3INSRIGF1RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220026444-A1 | METHODS FOR DIAGNOSING AND/OR TREATING ACUTE OR CHRONIC LIVER, KIDNEY OR LUNG DISEASE | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2022-01-27 | — | — | US | claimed |
| EP-3886851-A1 | METHODS FOR DIAGNOSING AND/OR TREATING ACUTE OR CHRONIC LIVER, KIDNEY OR LUNG DISEASE | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2021-10-06 | — | — | EP | claimed |
| CN-113271943-A | Method for diagnosing and/or treating acute or chronic liver, kidney or lung diseases | 比奥基内生物科学协会合作研究中心 | 2021-08-17 | — | — | CN | claimed |
| WO-2020109316-A1 | METHODS FOR DIAGNOSING AND/OR TREATING ACUTE OR CHRONIC LIVER, KIDNEY OR LUNG DISEASE | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2020-06-04 | — | — | WO | claimed |
| US-12285439-B2 | Methods for diagnosing and/or treating acute or chronic liver, kidney or lung disease | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2025-04-29 | — | — | US | disclosed |
| US-20240229041-A2 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF CNNM4 IN A CELL | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2024-07-11 | — | — | US | disclosed |
| US-20230265438-A1 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF CNNM4 IN A CELL | ASOCIACION CENTRO DE INVESTIG COOPERATIVA EN BIOCIENCIAS CIC BIOGUNE (ES) | 2023-08-24 | — | — | US | disclosed |
| EP-4158023-A1 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF CNNM4 IN A CELL | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2023-04-05 | — | — | EP | disclosed |
| US-20220026444-A1 | METHODS FOR DIAGNOSING AND/OR TREATING ACUTE OR CHRONIC LIVER, KIDNEY OR LUNG DISEASE | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2022-01-27 | — | — | US | disclosed |
| WO-2021239825-A1 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF CNNM4 IN A CELL | SILENCE THERAPEUTICS GMBH (DE) | 2021-12-02 | — | — | WO | disclosed |
| EP-3886851-A1 | METHODS FOR DIAGNOSING AND/OR TREATING ACUTE OR CHRONIC LIVER, KIDNEY OR LUNG DISEASE | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2021-10-06 | — | — | EP | disclosed |
| CN-113271943-A | Method for diagnosing and/or treating acute or chronic liver, kidney or lung diseases | 比奥基内生物科学协会合作研究中心 | 2021-08-17 | — | — | CN | disclosed |
| WO-2020109316-A1 | METHODS FOR DIAGNOSING AND/OR TREATING ACUTE OR CHRONIC LIVER, KIDNEY OR LUNG DISEASE | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2020-06-04 | — | — | WO | disclosed |
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
| WO-2010148351-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240229041-A2 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF CNNM4 IN A CELL | HNF4A, CDK4, CDKL4 | PTP4A3 2731/4885INSR 929/4885IGF1R 1049/4885 |
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | PIM2, PIM1, CDK2 | PTP4A3 1768/4885INSR 1642/4885IGF1R 522/4885 |
| US-20230265438-A1 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF CNNM4 IN A CELL | HNF4A, CDK4, CDKL4 | PTP4A3 2731/4885INSR 929/4885IGF1R 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.