Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | PRKACA | P17612 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12270293 | 0.90 | MAPT (0.48) | MAPTMAPK14GCGRFGFR1PRKACA | |
| SCHEMBL12270186 | 0.90 | MAPT (0.44) | MAPTMAPK14GCGRFGFR1PRKACA | |
| Piperazine SCHEMBL28105170 | 0.89 | MAPT (0.44) | MAPTMAPK14GCGRFGFR1PRKACA | |
| Pyridine SCHEMBL28104888 | 0.87 | MAPK14 (0.58) | MAPTMAPK14GCGRFGFR1PRKACA | |
| SCHEMBL8962658 | 0.87 | RPS6KA3 (0.56) | MAPTMAPK14GCGRRPS6KA3DYRK1A | |
| SCHEMBL2285019 | 0.87 | MAPK14 (0.68) | MAPTMAPK14GCGRPTGS2 | |
| SCHEMBL2285042 | 0.80 | IDO1 (0.54) | MAPK14IKBKBCHUKGAANOTUM | |
| SCHEMBL2285916 | 0.80 | HSD17B1 (0.48) | MAPK14CYP3A4 | |
| SCHEMBL8962438 | 0.78 | HPGD (0.61) | MAPTCHUKALDH1A1HSD17B10HPGD | |
| SCHEMBL11312239 | 0.75 | MAPT (0.48) | MAPTFGFR1PRKACARPS6KA3IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109320170-B | Temperature sensing discolours brick that permeates water | 厦门固泽环保科技有限公司 | 2021-06-04 | — | — | CN | claimed |
| EP-2758414-B1 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW SILICONES CORP (US) | 2018-11-21 | — | — | EP | claimed |
| CN-107935928-A | A kind of total diphenylpypazole and its preparation method and application | 鲁东大学 | 2018-04-20 | — | — | CN | claimed |
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | claimed |
| EP-2758414-A2 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | Dow Corning Corporation (US) | 2014-07-30 | — | — | EP | claimed |
| WO-2013043787-A2 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | claimed |
| EP-2205076-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER USING COX-2 INHIBITORS AND DUAL INHIBITORS OF EGFR ÝERBB1¨AND HER-2 ÝERBB2¨ | Tragara Pharmaceuticals, Inc. (US) | 2010-07-14 | — | — | EP | claimed |
| WO-2009042613-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER USING COX-2 INHIBITORS AND DUAL INHIBITORS OF EGFR [ERBB1] AND HER-2 [ERBB2] | TRAGARA PHARMACEUTICALS, INC. (US) | 2009-04-02 | — | — | WO | claimed |
| EP-0133061-A1 | Diphenylazomethines bearing an imidazolyl radical, their preparation and their therapeutical application | SYNTHELABO (FR) | 1985-02-13 | — | — | EP | claimed |
| JP-11246403-A | — | — | None | — | — | JP | disclosed |
| US-20250241567-A1 | SENSOR SYSTEM FOR OPTICAL DETECTION OF MULTIPLE ANALYTES | BLUEHALO, LLC | 2025-07-31 | — | — | US | disclosed |
| WO-2024088237-A1 | LUMINESCENT MATERIAL, USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME | 清华大学 | 2024-05-02 | — | — | WO | disclosed |
| CN-117546851-A | Herbicidal compositions containing uracil compounds of carboxylate fragments and uses thereof | 江苏中旗科技股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-116612964-A | Temporary leakage blocking method for transformer oil leakage | 道县航大电子科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| EP-0038536-A1 | Antiinflammatory 4,5-diaryl-alpha-(polyfluoroalkyl)-1H-pyrrole-2-methanamines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-10-28 | — | — | EP | disclosed |
| US-4267184-A | USEFUL FOR TREATING ARTHRITIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| US-4267190-A | AND METHOD OF ADMINISTERING TO MAMMALS FOR TREATMENT OF ARTHRITIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| EP-0025884-A1 | 4,5-Diaryl-alpha-polyfluoroalkyl-1H-pyrrole-2-methanols and 1-(4,5-diaryl-1H-pyrrol-2-yl)-polyfluoroalkanones, processes for preparing them and pharmaceutical compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-04-01 | — | — | EP | disclosed |
| EP-0005156-A1 | 4,5-diaryl-2-(substituted-thio)-pyrroles and their corresponding sulfoxides and sulfones, process for their preparation and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-3953433-A | REACTION PRODUCT COMPRISING BENZOPYRYLIUM SALT AND BENZOPYRAN | RICOH CO., LTD. (JA) | 1976-04-27 | — | — | US | disclosed |