SCHEMBL3424447

SCHEMBL3424447

CC(C)N(CC(=O)O)CP(=O)(O)O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FDPS P14324 2/20 0.35
FOLH1 Q04609 2/20 0.32
MVD P53602 2/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
GGH Q92820 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1463097 0.86 MEN1 (0.34) MEN1LMNAHPGDTSHRBLM
SCHEMBL10716346 0.84 FOLH1 (0.34) MEN1LMNAHPGDTSHRBLM
SCHEMBL10716340 0.84 FOLH1 (0.34) MEN1LMNAHPGDTSHRBLM
SCHEMBL9833755 0.82 FDPS (0.38) MEN1LMNAHPGDTSHRBLM
SCHEMBL10409147 0.81 MVD (0.32) MVD
SCHEMBL10482435 0.81 MVD (0.32) MEN1LMNAHPGDTSHRBLM
SCHEMBL29420575 0.80 FDPS (0.33) MEN1LMNAHPGDTSHRBLM
SCHEMBL156073 0.79 TDP1 (0.41) LMNATSHRBLMTDP1
SCHEMBL10482425 0.79 FDPS (0.36) MEN1LMNAHPGDTSHRBLM
SCHEMBL3838114 0.78 TDP1 (0.39) MEN1LMNAHPGDTSHRBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0221043-B1 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED AMINOMETHYLPHOSPHONIC ACIDS Monsanto Company (US) 1991-09-11 EP claimed
US-4804499-A Process for the preparation of N-substituted aminomethylphosphonic acids MONSANTO COMPANY (US) 1989-02-14 US claimed
EP-0221043-A1 Process for the preparation of N-substituted aminomethylphosphonic acids Monsanto Company (US) 1987-05-06 EP claimed
US-4657705-A Process for the preparation of N-substituted aminomethylphosphonic acids MONSANTO COMPANY (US) 1987-04-14 US claimed
EP-0216744-A2 The compound 1,4-diisopropyl-2,5-diketopiperazine Monsanto Company (US) 1987-04-01 EP claimed
EP-0216745-A1 Process for the preparation of N-substituted aminomethylphosphonic acids Monsanto Company (US) 1987-04-01 EP claimed
US-7750180-B2 Process for the preparation of N-phosphonomethylglycine and derivatives thereof MONSANTO TECHNOLOGY LLC (US) 2010-07-06 US disclosed
US-7297657-B2 Process for the preparation of N-(phosphonomethyl)glycine by oxidizing N-substituted N-(phosphonomethyl)glycine MONSANTO TECHNOLOGY LLC (US) 2007-11-20 US disclosed
EP-1716923-A1 Oxidation catalyst for making glyphosate Monsanto Technology, LLC (US) 2006-11-02 EP disclosed
EP-1664068-A2 PROCESS FOR THE PREPARATION OF N-PHOSPHONO-METHYLGLYCINE AND DERIVATIVES THEREOF Monsanto Technology, LLC (US) 2006-06-07 EP disclosed
EP-1062221-B1 PROCESS FOR MAKING GLYPHOSATE BY OXIDIZING N-SUBSTITUTED GLYPHOSATES MONSANTO TECHNOLOGY LLC (US) 2006-05-10 EP disclosed
EP-1520857-A1 Process for the preparation of N-(phosphonomethyl) glycine by oxidizing N-substituted N-(phosphonomethyl) glycine Monsanto Technology LLC (US) 2005-04-06 EP disclosed
US-20050054871-A1 Process for the preparation of N-phosphonomethylglycine and derivatives thereof MONSANTO TECHNOLOGY LLC 2005-03-10 US disclosed
EP-0186648-A1 Process for the preparation of glyphosate and glyphosate derivatives Monsanto Company (US) 1986-07-02 EP disclosed
EP-0186647-A1 Process for preparing glyphosate and glyphosate derivatives Monsanto Company (US) 1986-07-02 EP disclosed
US-4568432-A REACTING OXO-AMINES WITH CARBONYLPHOSPHONIC COMPOUND, THEN REDUCTION MONSANTO COMPANY (US) 1986-02-04 US disclosed
US-4471131-A POST EMERGENCE HERBICIDES MONSANTO COMPANY (US) 1984-09-11 US disclosed
US-4131448-A HERBICIDE MONSANTO COMPANY (US) 1978-12-26 US disclosed
US-4130412-A HERBICIDE MONSANTO COMPANY (US) 1978-12-19 US disclosed
US-4062669-A N-Organo-N-phosphonomethylglycine-N-oxides and plant growth regulant and phytotoxicant compositions containing same MONSANTO COMPANY (US) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054871-A1 Process for the preparation of N-phosphonomethylglycine and derivatives thereof PHOSPHO1, GNE, MPHOSPH6 MEN1 1141/4885LMNA 1967/4885HPGD 648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.