SCHEMBL3425372

SCHEMBL3425372

O=[C]Nc1cccc2cccnc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 4/20 0.56
ALOX15 P16050 2/20 0.56
HTT P42858 2/20 0.56
TDP1 Q9NUW8 5/20 0.53
POLB P06746 2/20 0.53
CYP3A4 P08684 2/20 0.51
CYP1A2 P05177 1/20 0.51
SLC40A1 Q9NP59 6/20 0.51
G6PD P11413 1/20 0.51
NFKBIA P25963 1/20 0.51
AGTR1 P30556 1/20 0.51
METAP2 P50579 1/20 0.51
METAP1 P53582 1/20 0.51
PAX8 Q06710 1/20 0.51
ATM Q13315 1/20 0.51
KDR P35968 1/20 0.51
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MAPT P10636 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704782 0.81 GLO1 (0.51) GLO1ALOX15HTTTDP1POLB
SCHEMBL4546341 0.79 TDP1 (0.62) GLO1ALOX15HTTTDP1POLB
SCHEMBL379216 0.78 GLO1 (0.59) GLO1ALOX15HTTTDP1POLB
SCHEMBL3156796 0.78 MAPT (0.63) GLO1ALOX15HTTTDP1POLB
Hydrochloric Acid SCHEMBL28172351 0.77 TDP1 (0.60) GLO1ALOX15HTTTDP1POLB
SCHEMBL7774451 0.75 CYP3A4 (0.61) GLO1ALOX15HTTTDP1POLB
SCHEMBL31130165 0.75 CYP3A4 (0.61) GLO1ALOX15HTTTDP1POLB
SCHEMBL17749155 0.75 GLO1 (0.56) GLO1ALOX15HTTTDP1POLB
SCHEMBL13337941 0.75 MEN1 (0.56) GLO1ALOX15HTTTDP1POLB
SCHEMBL27938447 0.75 HTT (0.56) GLO1ALOX15HTTTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743061-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS Pascal Biosciences Inc. (CA) 2020-12-02 EP claimed
WO-2019144126-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS PASCAL BIOSCIENCES INC. (CA) 2019-07-25 WO claimed
US-5633364-A N4 -substituted 2'-deoxycytidine compounds, oligonucleotides including N4 -labeled 2'-deoxycytidines, and a process for making oligonucleotides with N-modified 2'-deoxycytidines AMOCO CORPORATION (US) 1997-05-27 US claimed
US-20230270763-A1 METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES PASCAL BIOSCIENCES INC (CA) 2023-08-31 US disclosed
WO-2022006498-A1 METHOD OF TREATING CORONAVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES PASCAL BIOSCIENCES INC. (CA) 2022-01-06 WO disclosed
US-20210038559-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS PASCAL BIOSCIENCES INC. (CA) 2021-02-11 US disclosed
EP-3743061-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS Pascal Biosciences Inc. (CA) 2020-12-02 EP disclosed
WO-2019144126-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS PASCAL BIOSCIENCES INC. (CA) 2019-07-25 WO disclosed
CN-104220065-A Substituted prolines/piperidines as orexin receptor antagonists EOLAS THERAPEUTICS INC 2014-12-17 CN disclosed
EP-2233493-A1 Macrolides Pfizer Products Inc. (US) 2010-09-29 EP disclosed
US-5633364-A N4 -substituted 2'-deoxycytidine compounds, oligonucleotides including N4 -labeled 2'-deoxycytidines, and a process for making oligonucleotides with N-modified 2'-deoxycytidines AMOCO CORPORATION (US) 1997-05-27 US disclosed
US-5405950-A N4 -substituted cytidines and process for incorporation into an oligonucleotides AMOCO CORPORATION (US) 1995-04-11 US disclosed
EP-0518961-A1 DERIVATIVES OF GLYCINAMIDE, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Aventis Pharma S.A. (FR) 1992-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270763-A1 METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES CNR1, CNR2, SARS1 GLO1 3715/4885ALOX15 1124/4885HTT 2961/4885
US-20210038559-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS CNR1, CNR2, CD74 GLO1 2984/4885ALOX15 881/4885HTT 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.