Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525691 | 0.77 | HTR2A (0.35) | HTR2AANPEPMAOAMAOBACP3 | |
| SCHEMBL5749663 | 0.71 | HTR2A (0.38) | HTR2AANPEPHRH1RETHTR2C | |
| SCHEMBL6763552 | 0.71 | HTR2A (0.38) | HTR2AANPEPMAOAMAOBACP3 | |
| SCHEMBL6629432 | 0.71 | HTR2A (0.48) | HTR2AANPEPHRH1RETHTR2C | |
| SCHEMBL528662 | 0.71 | HTR2A (0.38) | HTR2AANPEPMAOAMAOBACP3 | |
| SCHEMBL5751646 | 0.71 | HTR2A (0.38) | HTR2AHRH1HTR2C | |
| SCHEMBL3078945 | 0.71 | HTR2A (0.38) | HTR2AANPEPMAOAMAOBACP3 | |
| SCHEMBL7680505 | 0.71 | HTR2A (0.34) | HTR2AANPEPACP3HRH1RET | |
| SCHEMBL8180890 | 0.70 | TSHR (0.42) | ACP3HDAC4HDAC7HDAC5CYP1A2 | |
| SCHEMBL23645056 | 0.69 | ACP3 (0.35) | HTR2AANPEPMAOAMAOBACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718671-B2 | Substituted arylthiourea derivatives useful as inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. (US) | 2010-05-18 | — | — | US | claimed |