Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22328101 | 0.77 | HTR2A (0.35) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL6629432 | 0.71 | HTR2A (0.48) | HTR2ARETHTR2CHRH1ANPEP | |
| SCHEMBL6763552 | 0.71 | HTR2A (0.38) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL5751646 | 0.71 | HTR2A (0.38) | HTR2AHTR2CHRH1PRCPCHRNB2 | |
| SCHEMBL528662 | 0.71 | HTR2A (0.38) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL3078945 | 0.71 | HTR2A (0.38) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL3426562 | 0.71 | HTR2A (0.38) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL7680505 | 0.71 | HTR2A (0.34) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL3389204 | 0.68 | HTR2A (0.35) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL20536825 | 0.67 | HTR2A (0.61) | HTR2AHTR2CHRH1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660427-A4 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |