SCHEMBL3426760

SCHEMBL3426760

O=C(c1ccccc1)c1ccccc1N=Nc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.59
GAA P10253 2/20 0.55
MAPT P10636 2/20 0.55
ALDH1A1 P00352 2/20 0.54
IDE P14735 1/20 0.50
ATM Q13315 3/20 0.47
CDC25B P30305 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SRD5A2 P31213 1/20 0.46
HSP90AA1 P07900 1/20 0.46
PKM P14618 1/20 0.46
CCR6 P51684 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TLR9 Q9NR96 1/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NR4A1 P22736 1/20 0.46
CYP2C8 P10632 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29042744 0.92 IDE (0.57) AKR1C3GAAMAPTALDH1A1IDE
SCHEMBL29042746 0.92 IDE (0.57) AKR1C3GAAMAPTALDH1A1IDE
SCHEMBL31346158 0.92 IDE (0.57) AKR1C3GAAMAPTALDH1A1IDE
SCHEMBL16602419 0.88 MAPT (0.53) AKR1C3GAAMAPTALDH1A1IDE
SCHEMBL1535311 0.85 AKR1C3 (0.57) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL8984215 0.83 NAPRT (0.49) AKR1C3GAAMAPTALDH1A1IDE
SCHEMBL8958641 0.83 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL11812213 0.82 MAPT (0.47) AKR1C3GAAMAPTALDH1A1IDE
SCHEMBL819015 0.82 AKR1C3 (0.53) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL11811452 0.81 AKR1C3 (0.44) AKR1C3GAAMAPTALDH1A1IDE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115612699-A Copolymer membrane and enzymatic self-assembly synthesis method and application thereof at gas-liquid interface 中国科学院天津工业生物技术研究所 2023-01-17 CN disclosed
CN-115612114-A Copolymer membrane and enzymatic self-assembly synthesis method and application thereof 中国科学院天津工业生物技术研究所 2023-01-17 CN disclosed
CN-115612403-A Self-assembly strong-adhesion copolymer film, film coating method and application 中国科学院天津工业生物技术研究所 2023-01-17 CN disclosed
CN-115175934-A Antigen binding proteins targeting consensus neoantigens 磨石生物公司 2022-10-11 CN disclosed
US-7674472-B2 Method for preparing a cosmetic composition and cosmetic composition prepared by this method CONOPCO, INC. (US) 2010-03-09 US disclosed
WO-2009121757-A2 A NOVEL PERSONAL WASH BAR UNILEVER PLC (GB) 2009-10-08 WO disclosed
US-20090253602-A1 Novel personal wash bar CONOPCO, INC. D/B/A UNILEVER 2009-10-08 US disclosed
EP-1905484-A1 Cosmetic composition and preparation method therefor Unilever PLC (GB) 2008-04-02 EP disclosed
US-20060093569-A1 Method for preparing a cosmetic composition and cosmetic composition prepared by this method CONOPCO, INC., D/B/A UNILEVER 2006-05-04 US disclosed
EP-1505952-A1 METHOD FOR PREPARING A COSMETIC COMPOSITION AND COSMETIC COMPOSITION PREPARED BY THIS METHOD UNILEVER N.V. (NL) 2005-02-16 EP disclosed
US-20050019351-A1 Cosmetic composition and preparation method therefor CONOPCO, INC. 2005-01-27 US disclosed
US-20050013837-A1 Cosmetic composition comprising a fatty alcohol material and preparation method therefor CONOPCO, INC. 2005-01-20 US disclosed
US-20050002971-A1 Cosmetic composition comprising a fatty acid material and preparation method therefor CONOPCO, INC. 2005-01-06 US disclosed
EP-1458348-A1 COSMETIC COMPOSITION COMPRISING A FATTY ACID MATERIAL AND PREPARATION METHOD THEREFOR UNILEVER N.V. (NL) 2004-09-22 EP disclosed
EP-1448161-A1 COSMETIC COMPOSITION AND PREPARATION METHOD THEREFORE UNILEVER N.V. (NL) 2004-08-25 EP disclosed
EP-1448160-A1 COSMETIC COMPOSITION COMPRISING A FATTY ALCOHOL MATERIAL AND PREPARATION METHOD THEREFOR UNILEVER N.V. (NL) 2004-08-25 EP disclosed
WO-2003097003-A1 METHOD FOR PREPARING A COSMETIC COMPOSITION AND COSMETIC COMPOSITION PREPARED BY THIS METHOD UNILEVER N.V. (NL) 2003-11-27 WO disclosed
WO-2003045346-A1 COSMETIC COMPOSITION COMPRISING A FATTY ALCOHOL MATERIAL AND PREPARATION METHOD THEREFOR UNILEVER N.V. (NL) 2003-06-05 WO disclosed
WO-2003045347-A1 COSMETIC COMPOSITION AND PREPARATION METHOD THEREFOR UNILEVER N.V. (NL) 2003-06-05 WO disclosed
WO-2003045348-A1 COSMETIC COMPOSITION COMPRISING A FATTY ACID MATERIAL AND PREPARATION METHOD THEREFOR UNILEVER N.V. (NL) 2003-06-05 WO disclosed