Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27359663 | 0.84 | HTT (0.42) | SMN1; SMN2HTTSSTR4KMT2AL3MBTL1 | |
| SCHEMBL23141464 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTSSTR4KMT2AL3MBTL1 | |
| SCHEMBL21570110 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2SSTR4MAPK1KMT2AL3MBTL1 | |
| SCHEMBL3417583 | 0.74 | POLB (0.50) | SMN1; SMN2MAPK1KMT2AKDM5AKDM4C | |
| SCHEMBL28293147 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2HTTSSTR4KMT2AL3MBTL1 | |
| SCHEMBL1357600 | 0.73 | — | — | |
| SCHEMBL24159298 | 0.71 | SSTR4 (0.42) | HTTSSTR4KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL10959724 | 0.70 | MAPT (0.53) | SMN1; SMN2KMT2AL3MBTL1NPC1CYP1A2 | |
| SCHEMBL23158215 | 0.70 | — | — | |
| SCHEMBL16303536 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2988321-B1 | CLEANING LIQUID COMPOSITION | KANTO KAGAKU (JP) | 2019-03-20 | — | — | EP | claimed |
| WO-2010051926-A2 | NEW HALOGEN-SUBSTITUTED BONDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-05-14 | — | — | WO | disclosed |
| EP-0023707-B1 | SUBSTITUTED TETRAAZATRICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0066774-B1 | 1,4,9,10-TETRAHYDROPYRAZOLO(4,3-E)PYRIDO(3,2-B)(1,4)DIAZEPIN-10-ONES, PROCESS FOR THEIR PREPARATION AND MEDICINAL PREPARATIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-12-12 | — | — | EP | disclosed |
| EP-0066774-A1 | 1,4,9,10-Tetrahydropyrazolo(4,3-e)pyrido(3,2-b)(1,4)diazepin-10-ones, process for their preparation and medicinal preparations containing them | Dr. Karl Thomae GmbH (DE) | 1982-12-15 | — | — | EP | disclosed |
| EP-0064775-A1 | Substituted tetraazatricyclic compounds, process for their preparation and their use | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-11-17 | — | — | EP | disclosed |
| EP-0023707-A1 | Substituted tetraazatricyclic compounds, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |