SCHEMBL3427358

SCHEMBL3427358

OCc1ccc(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.35
CA1 P00915 8/20 0.35
CHKA P35790 1/20 0.34
KIF11 P52732 1/20 0.34
STS P08842 1/20 0.33
PRKCA P17252 1/20 0.32
TSHR P16473 1/20 0.32
S1PR1 P21453 2/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
TNNC1 P63316 3/20 0.30
SGPL1 O95470 1/20 0.30
S1PR4 O95977 1/20 0.30
GPR183 P32249 1/20 0.30
CERS2 Q96G23 1/20 0.30
S1PR3 Q99500 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3426890 1.00 CA2 (0.35) CA2CA1CHKAKIF11STS
SCHEMBL3045440 0.98 CHKA (0.35) CA2CA1CHKAKIF11STS
SCHEMBL7156898 0.85 ESR1 (0.46) CA2
SCHEMBL3038595 0.84 CHKA (0.38) CA2CA1CHKAKIF11TSHR
SCHEMBL18421431 0.81 CA2 (0.33) CA2CA1STS
SCHEMBL3963217 0.81 TAAR1 (0.41) CA2CA1
SCHEMBL12727813 0.81 CYP1A2 (0.41) CA2CA1CHKA
SCHEMBL12971204 0.81 CA1 (0.33) CA2CA1STS
SCHEMBL3396819 0.81 CA1 (0.39) CA2CA1STS
SCHEMBL28495789 0.81 CA1 (0.33) CA2CA1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
US-20150225339-A1 FLUORINATED POLYMERIZABLE COMPOUND BASF SE (DE) 2015-08-13 US disclosed
EP-2904030-A1 FLUORINATED POLYMERIZABLE COMPOUND BASF SE (DE) 2015-08-12 EP disclosed
WO-2014053636-A1 FLUORINATED POLYMERIZABLE COMPOUND BASF SE (DE) 2014-04-10 WO disclosed
US-20100324205-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2010-12-23 US disclosed
EP-2247669-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION Construction Research & Technology GmbH (DE) 2010-11-10 EP disclosed
US-20090240004-A1 FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-09-24 US disclosed
WO-2009095325-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-08-06 WO disclosed
US-20090198000-A1 Liquid fluorine-containing and two-component compositions for the surface treatment of mineral and non-mineral substrates EVONIK DEGUSSA GMBH (DE) 2009-08-06 US disclosed
EP-2085442-A1 Compounds containing fluoride with improved surface characteristics Evonik Degussa GmbH (DE) 2009-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150225339-A1 FLUORINATED POLYMERIZABLE COMPOUND FRK, AFF2, AFF1 CA2 1277/4885CA1 607/4885CHKA 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.