Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 1/20 | 0.64 |
| ▸ | MC3R | P41968 | 1/20 | 0.64 |
| ▸ | MC1R | Q01726 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | AANAT | Q16613 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660463 | 0.87 | MC5R (0.66) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL29489675 | 0.87 | MC5R (0.66) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL9542634 | 0.83 | HTR2A (0.63) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL7037221 | 0.83 | MC5R (0.73) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL17232881 | 0.83 | MC5R (0.83) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL7970552 | 0.81 | MC5R (0.81) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL7559256 | 0.80 | SMN1; SMN2 (0.67) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL5939865 | 0.80 | MC5R (0.64) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL7144840 | 0.79 | HTR2A (0.58) | MC5RMC3RMC1RHTR2AKMT2A | |
| SCHEMBL4017867 | 0.79 | MC5R (0.71) | MC5RMC3RMC1RHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015703-A2 | NOVEL 6-O-SUBSTITUTED 15-MEMBERED 8A- AND 9A-LACTAMS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2010-02-11 | — | — | WO | disclosed |