Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.81 |
| ▸ | MC3R | P41968 | 2/20 | 0.81 |
| ▸ | MC1R | Q01726 | 2/20 | 0.81 |
| ▸ | G6PD | P11413 | 1/20 | 0.79 |
| ▸ | HTR2A | P28223 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | HTR1A | P08908 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | HTR6 | P50406 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | HTR1D | P28221 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17232881 | 0.98 | MC5R (0.83) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL6165432 | 0.90 | MC5R (0.71) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL12978083 | 0.90 | MC1R (0.71) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL13255375 | 0.90 | MC5R (0.71) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL14960999 | 0.90 | HTR2A (0.79) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL25029618 | 0.90 | MC5R (0.71) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL4017867 | 0.90 | MC5R (0.71) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL798249 | 0.89 | MC1R (1.00) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL20689754 | 0.89 | G6PD (0.83) | MC5RMC3RMC1RG6PDHTR2A | |
| Hydrochloric Acid SCHEMBL3593245 | 0.89 | MC5R (0.69) | MC5RMC3RMC1RG6PDHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |