Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18255967 | 1.00 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL18255978 | 1.00 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL3400424 | 1.00 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL18255973 | 0.92 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL18255971 | 0.92 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL18255976 | 0.90 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL18255977 | 0.90 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL18255980 | 0.89 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL18255979 | 0.89 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL632598 | 0.88 | SIGMAR1 (0.42) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505750-B2 | 5-aminocyclylmethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2016-11-29 | — | — | US | claimed |
| US-9505750-B2 | 5-aminocyclylmethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2016-11-29 | — | — | US | disclosed |
| EP-2245028-A1 | 5-AMINOCYCLYLMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009077989-A1 | 5-AMINOCYCLYLMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-06-25 | — | — | WO | disclosed |