Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272693 | 0.85 | HDAC1 (0.63) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8532983 | 0.83 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL13314553 | 0.82 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8532136 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9479087 | 0.81 | HDAC1 (0.70) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29214182 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7218629 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL30914584 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9670430 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7023747 | 0.81 | HDAC1 (0.65) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146351-A1 | INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-12-23 | — | — | WO | disclosed |