Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 18/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285176 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BSMPD3 | |
| SCHEMBL1285050 | 0.90 | MTNR1A (0.54) | MTNR1AMTNR1BUSP30 | |
| SCHEMBL1285571 | 0.89 | MTNR1A (0.42) | MTNR1AMTNR1BUSP30SMPD3 | |
| SCHEMBL1696511 | 0.89 | MTNR1A (0.42) | MTNR1AMTNR1BUSP30SMPD3 | |
| SCHEMBL1285121 | 0.89 | MTNR1A (0.56) | MTNR1AMTNR1BUSP30 | |
| SCHEMBL1285845 | 0.89 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL1696512 | 0.88 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL1285591 | 0.88 | MTNR1A (0.48) | MTNR1AMTNR1BUSP30 | |
| SCHEMBL1284713 | 0.87 | MTNR1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL1696499 | 0.87 | PIM1 (0.46) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266975-A1 | 1-(2-alkyl-2,3-dihydro-benzofuran-4-yl)-pyrrolidin-3-ylamine acyl compounds | Ferrer Internacional, S.A. (ES) | 2010-12-29 | — | — | EP | claimed |
| WO-2010145989-A1 | 1-(2-ALKYL-2,3-DIHYDRO-BENZOFURAN-4-YL)-PYRROLIDIN-3-YLAMINE ACYL COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2010-12-23 | — | — | WO | claimed |
| EP-2266975-A1 | 1-(2-alkyl-2,3-dihydro-benzofuran-4-yl)-pyrrolidin-3-ylamine acyl compounds | Ferrer Internacional, S.A. (ES) | 2010-12-29 | — | — | EP | disclosed |
| WO-2010145989-A1 | 1-(2-ALKYL-2,3-DIHYDRO-BENZOFURAN-4-YL)-PYRROLIDIN-3-YLAMINE ACYL COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2010-12-23 | — | — | WO | disclosed |