Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamate SCHEMBL9451526 | 0.81 | EPHX1 (0.51) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL9451522 | 0.80 | POLB (0.49) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL13310041 | 0.79 | EPHX1 (0.53) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL13310042 | 0.79 | EPHX1 (0.53) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL686723 | 0.79 | EPHX1 (0.53) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL688459 | 0.79 | CA1 (0.54) | EPHX1CXCR1CXCR2PTGS1PTGS2 | |
| SCHEMBL1275322 | 0.79 | GRIA4 (0.56) | LMNACYP2C9ALDH1A1TSHRCA12 | |
| SCHEMBL7164190 | 0.77 | CA2 (0.43) | ALOX5HTR2ACA12CA1CA2 | |
| SCHEMBL6219939 | 0.77 | CA2 (0.43) | ALOX5HTR2ACA12CA1CA2 | |
| SCHEMBL12327017 | 0.76 | TAAR1 (0.56) | EPHX1CXCR1CXCR2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |
| US-20060258730-A1 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE S.P.A. (IT) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258730-A1 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | CCR8, CCR1, CXCR1 | EPHX1 1244/4885CXCR1 3/4885CXCR2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.