Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19271011 | 0.83 | POLB (0.43) | ALDH1A1CYP3A4EPHX1 | |
| SCHEMBL19315994 | 0.82 | NOS3 (0.46) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL22185917 | 0.82 | NOS3 (0.46) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL2283867 | 0.82 | NOS3 (0.46) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL17864297 | 0.82 | NOS3 (0.46) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL12262010 | 0.82 | NOS3 (0.46) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL7992146 | 0.78 | NOS3 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL6065495 | 0.78 | NOS3 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL3234896 | 0.78 | NOS3 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL12262005 | 0.78 | NOS3 (0.46) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120118291-A | Aromatic amine curing agent composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| EP-2139936-B1 | POLYURETHANE COMPOUND CONTAINING ASYMMETRIC DIALDIMINE | SIKA TECH AG (CH) | 2019-11-13 | — | — | EP | claimed |
| EP-2132245-B1 | COMPOUND WITH LOW ISOCYANATE-MONOMER CONTENT CONTAINING ISOCYANATE AND ALDIMINO GROUPS | SIKA TECH AG (CH) | 2017-11-15 | — | — | EP | claimed |
| US-9290608-B2 | Asymmetric dialdimine-containing polyurethane composition | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | claimed |
| US-20140322531-A1 | ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2014-10-30 | — | — | US | claimed |
| US-8816037-B2 | Asymmetric dialdimine-containing polyurethane composition | SIKA TECHNOLOGY AG (CH) | 2014-08-26 | — | — | US | claimed |
| US-20120142870-A1 | Isocyanate- and Aldimine Group- Carrying Compounds with a Low Isocyanate Monomer Content | SIKA TECHNOLOGY AG (CH) | 2012-06-07 | — | — | US | claimed |
| US-20100021743-A1 | ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2010-01-28 | — | — | US | claimed |
| US-20100015450-A1 | Isocyanate-and Aldimine Group-Carrying Compounds With a Low Isocyanate Monomer Content | SIKA TECHNOLOGY AG (CH) | 2010-01-21 | — | — | US | claimed |
| EP-2139936-A1 | ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION | Sika Technology AG (CH) | 2010-01-06 | — | — | EP | claimed |
| EP-2132245-A1 | ISOCYANATE- AND ALDIMINE GROUP-CARRYING COMPOUNDS WITH A LOW ISOCYANATE MONOMER CONTENT | Sika Technology AG (CH) | 2009-12-16 | — | — | EP | claimed |
| WO-2008116901-A1 | ISOCYANATE- AND ALDIMINE GROUP-CARRYING COMPOUNDS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | claimed |
| WO-2008116902-A1 | ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | claimed |
| EP-1975186-A1 | Compound with low isocyanate-monomer content containing isocyanate and aldimino groups | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | claimed |
| EP-1975189-A1 | Polyurethane compound containing asymmetric dialdimine | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | claimed |
| CN-120118291-A | Aromatic amine curing agent composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-2139936-B1 | POLYURETHANE COMPOUND CONTAINING ASYMMETRIC DIALDIMINE | SIKA TECH AG (CH) | 2019-11-13 | — | — | EP | disclosed |
| WO-2008116901-A1 | ISOCYANATE- AND ALDIMINE GROUP-CARRYING COMPOUNDS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |
| EP-1975186-A1 | Compound with low isocyanate-monomer content containing isocyanate and aldimino groups | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| EP-1975189-A1 | Polyurethane compound containing asymmetric dialdimine | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142870-A1 | Isocyanate- and Aldimine Group- Carrying Compounds with a Low Isocyanate Monomer Content | IDH3A, ICAM1, VIM | ALDH1A1 19/4885HTR6 4208/4885GFER 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.