Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26450841 | 0.80 | NOTUM (0.66) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL6580790 | 0.79 | HDAC3 (0.71) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL13059439 | 0.79 | HDAC3 (0.67) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL9138101 | 0.79 | HDAC3 (0.71) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL1658749 | 0.79 | HDAC3 (0.56) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL4072403 | 0.77 | HPGD (0.70) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL5389653 | 0.77 | HPGD (0.70) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL6228768 | 0.77 | HDAC3 (0.68) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL794685 | 0.76 | HDAC3 (0.72) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL13487712 | 0.76 | HDAC3 (0.67) | HDAC3HDAC1HDAC10HDAC11HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-A2 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | Edison Pharmaceuticals, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009111576-A2 | 2-SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | EDISON PHARMACEUTICALS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |