⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745040 | 0.91 | KDM4E (0.32) | — | |
| SCHEMBL24951938 | 0.90 | HRH4 (0.39) | — | |
| SCHEMBL3186493 | 0.87 | HRH3 (0.42) | — | |
| Hydrochloric Acid SCHEMBL6897821 | 0.85 | HRH4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL27567168 | 0.85 | HRH4 (0.41) | — | |
| SCHEMBL6967400 | 0.84 | — | — | |
| SCHEMBL8851861 | 0.84 | NOS3 (0.36) | — | |
| SCHEMBL18248982 | 0.84 | PIK3CD (0.53) | — | |
| SCHEMBL8851859 | 0.84 | — | — | |
| SCHEMBL6961851 | 0.82 | CHRM2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463452-B1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC (US) | 2025-07-30 | — | — | EP | disclosed |
| US-12344600-B2 | c-Myc mRNA translation modulators and uses thereof in the treatment of cancer | ANIMA BIOTECH INC. (US) | 2025-07-01 | — | — | US | disclosed |
| US-20250109128-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2025-04-03 | — | — | US | disclosed |
| US-20200331910-A1 | Mammalian and Bacterial Nitric Oxide Synthase Inhibitors | UNIV NORTHWESTERN (US) | 2020-10-22 | — | — | US | disclosed |
| US-10759791-B2 | Mammalian and bacterial nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2020-09-01 | — | — | US | disclosed |
| US-9951014-B2 | Mammalian and bacterial nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160122302-A1 | Mammalian and Bacterial Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY | 2016-05-05 | — | — | US | disclosed |
| US-8183380-B2 | 2-aminoquinolines | HOFFMANN-LA ROCHE INC. (US) | 2012-05-22 | — | — | US | disclosed |
| EP-2262789-A1 | 2-AMINOQUINOLINES | F. Hoffmann-La Roche AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| EP-1578409-B1 | USE OF ADENOSINE A2A RECEPTOR ANTAGONISTS FOR TREATMENT OR PREVENTION OF EXTRA-PYRAMIDAL SYNDROME | SCHERING CORP (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| CN-1063442-C | Aminothiazole derivatives, drug containing the same and intermediate in the production of the compounds | ZERIA PHARM CO LTD (JP) | 2001-03-21 | — | — | CN | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| CN-1184471-A | Aminothiazole derivatives, drug containing the same and intermediate in the production of the compounds | ZERIA PHARM CO LTD (JP) | 1998-06-10 | — | — | CN | disclosed |
| CN-1021441-C | PROCESS FOR PREPARATION OF NEW BENZAMIDES | ILE DE FRANCE (FR) | 1993-06-30 | — | — | CN | disclosed |
| US-5010108-A | Treatment of gastrointestinal disorders | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1991-04-23 | — | — | US | disclosed |
| EP-0411494-A2 | Ergoline derivatives having dopaminergic activity | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1991-02-06 | — | — | EP | disclosed |
| EP-0333073-A2 | N-cycloalkylaminoethylbenzamide derivatives, their synthesis and pharmaceutical preparations | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |
| CN-86105682-A | Novel benzamides, process for their preparation and their use in therapy | — | 1987-02-04 | — | — | CN | disclosed |