Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15052376 | 0.79 | RECQL (0.35) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL22289685 | 0.72 | — | — | |
| SCHEMBL3430642 | 0.72 | KDM4E (0.33) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL10260750 | 0.67 | KDM4E (0.35) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL558164 | 0.67 | TSHR (0.37) | ALDH1A1TSHR | |
| SCHEMBL193133 | 0.66 | ALDH1A1 (0.39) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL1967465 | 0.65 | KDM4E (0.35) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL1679899 | 0.63 | — | — | |
| SCHEMBL3430041 | 0.62 | SRC (0.35) | ALDH1A1KDM4ERECQL | |
| SCHEMBL2912781 | 0.61 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146351-A1 | INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-12-23 | — | — | WO | disclosed |