SCHEMBL3430653

SCHEMBL3430653

Cc1cccc(-c2cc(NC[C@H](O)c3ccccc3)ncn2)c1C

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13663442 0.82 FAAH (0.75) FAAH
SCHEMBL4296770 0.82 FAAH (0.75) FAAH
SCHEMBL3427713 0.81 FAAH (0.66) FAAH
SCHEMBL4291985 0.81 FAAH (1.00) FAAH
SCHEMBL4294760 0.80 FAAH (1.00) FAAH
SCHEMBL13748665 0.80 FAAH (0.80) FAAH
SCHEMBL3431292 0.80 FAAH (0.83) FAAH
SCHEMBL4293448 0.80 FAAH (1.00) FAAH
SCHEMBL4298414 0.80 FAAH (0.82) FAAH
SCHEMBL13663503 0.80 FAAH (0.82) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2254415-A1 ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE Janssen Pharmaceutica, N.V. (BE) 2010-12-01 EP claimed
WO-2009105220-A1 ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2009-08-27 WO claimed