Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609735 | 1.00 | EPHX1 (0.78) | EPHX1ALDH1A1CYP1A2TDP1RAD52 | |
| SCHEMBL859151 | 1.00 | EPHX1 (0.78) | EPHX1ALDH1A1CYP1A2TDP1RAD52 | |
| SCHEMBL9263734 | 0.96 | EPHX1 (0.71) | EPHX1ALDH1A1CYP1A2TDP1RAD52 | |
| SCHEMBL5609230 | 0.93 | EPHX1 (0.66) | EPHX1ALDH1A1CYP1A2TDP1RAD52 | |
| SCHEMBL3854176 | 0.93 | EPHX1 (0.66) | EPHX1ALDH1A1CYP1A2TDP1TSHR | |
| SCHEMBL459853 | 0.93 | EPHX1 (0.66) | EPHX1ALDH1A1CYP1A2TDP1RAD52 | |
| SCHEMBL1628137 | 0.92 | EPHX1 (0.66) | EPHX1ALDH1A1 | |
| SCHEMBL25303980 | 0.88 | EPHX1 (1.00) | EPHX1ALDH1A1CYP1A2TDP1RAD52 | |
| SCHEMBL2731115 | 0.88 | EPHX1 (1.00) | EPHX1ALDH1A1CYP1A2TDP1RAD52 | |
| SCHEMBL11122975 | 0.88 | EPHX1 (1.00) | EPHX1ALDH1A1CYP1A2TDP1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071432-A1 | COMPOSITION FOR AND TREATMENT OF INFLAMMATORY BOWEL DISEASE BY COLON ADMINISTRATION OF N-ACETYLGLUCOSAMINE | Glucogenics Pharmaceuticals Inc. (CA) | 2001-01-31 | — | — | EP | claimed |
| WO-1999053929-A1 | COMPOSITION FOR AND TREATMENT OF INFLAMMATORY BOWEL DISEASE BY COLON ADMINISTRATION OF N-ACETYLGLUCOSAMINE | GLUCOGENICS PHARMACEUTICALS INC. (CA) | 1999-10-28 | — | — | WO | claimed |
| WO-2020142693-A1 | TREATMENT OF THYMIC STROMAL LYMPHOPOIETIN (TSLP) RELATED DISEASES BY INHIBITION OF LONG-FORM TSLP TRANSCRIPTS | EMPIRICO INC. (US) | 2020-07-09 | — | — | WO | disclosed |
| EP-2259772-A2 | CCR5 ANTAGONISTS AS PROPHYLACTICS FOR PREVENTING HIV INFECTION AND METHODS OF INHIBITING TRANSMISSION OF SAME | Schering Corporation (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009111218-A2 | CCR5 ANTAGONISTS AS PROPHYLACTICS FOR PREVENTING HIV INFECTION AND METHODS OF INHIBITING TRANSMISSION OF SAME | SCHERING CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |