SCHEMBL459853

SCHEMBL459853

CCC[CH]CCCCCCCC1CCO1

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.66
ALDH1A1 P00352 2/20 0.44
CYP1A2 P05177 2/20 0.35
TDP1 Q9NUW8 1/20 0.31
RAD52 P43351 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5609230 1.00 EPHX1 (0.66) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL5608421 0.95 EPHX1 (0.59) EPHX1ALDH1A1
SCHEMBL859151 0.93 EPHX1 (0.78) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL5609735 0.93 EPHX1 (0.78) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL3430826 0.93 EPHX1 (0.78) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL9263734 0.89 EPHX1 (0.71) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL17255663 0.87 EPHX1 (0.62) EPHX1ALDH1A1CYP1A2
SCHEMBL3854176 0.85 EPHX1 (0.66) EPHX1ALDH1A1CYP1A2TDP1
SCHEMBL1628137 0.85 EPHX1 (0.66) EPHX1ALDH1A1
SCHEMBL6050812 0.85 ALDH1A1 (0.63) EPHX1ALDH1A1CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101732711-A Preparation of nose-spraying flu immunization pentavalent or multivalent inactivated vaccine and application thereof INST MICROBIOLOGY & EPIDEMIOLOGY ACADEMY MILITARY MEDICAL SCIENCES PLA 2010-06-16 CN claimed
US-20240108683-A1 Method for Side Effect Reduction in the Use of Statins Via Physiologically Synthesized Glutathione PROIMMUNE CO LLC (US) 2024-04-04 US disclosed
EP-3193824-B1 A COMPOSITION FOR USE IN TREATING HYPERLIPIDEMIA, HYPERCHOLESTEROLEMIA AND/OR HYPERTRIGLYCERIDEMIA VIA PHYSIOLOGICALLY SYNTHESISED GLUTATHIONE THE PROIMMUNE COMPANY LLC (US) 2023-07-05 EP disclosed
EP-3154547-B1 PYRIMIDINE COMPOUNDS AND METHODS USING THE SAME YUMA THERAPEUTICS INC (US) 2023-06-07 EP disclosed
CN-114269719-A Urea derivatives as CB1 allosteric modulators RTI国际 2022-04-01 CN disclosed
US-20220047504-A1 ORAL DISSOLVABLE FILM WITH PORES EXTENDING THERETHROUGH CURE PHARMACEUTICAL HOLDING CORP. (US) 2022-02-17 US disclosed
US-20220023198-A1 ORAL SOLUBLE FILM CONTAINING SILDENAFIL CITRATE CURE PHARMACEUTICAL HOLDING CORP. (US) 2022-01-27 US disclosed
US-11179331-B1 Oral soluble film containing sildenafil citrate CURE PHARMACEUTCAI HOLDING CORP (US) 2021-11-23 US disclosed
US-20210322306-A1 ORAL DISSOLVABLE FILM WITH HIGH LOAD OF POLYMERIC BINDER CURE PHARMACEUTICAL HOLDING CORP. (US) 2021-10-21 US disclosed
EP-3829566-A2 COMPOSITIONS AND METHODS FOR TREATING THE EYE Johnson & Johnson Surgical Vision, Inc. (US) 2021-06-09 EP disclosed
US-20070025948-A1 Dilution-type sterilizer composition DAINIPPON SUMITOMO PHARMA CO. LTD (JP) 2007-02-01 US disclosed
US-20060034871-A1 Immunogenic compositions for Chlamydia trachomatis CHIRON CORPORATION (US) 2006-02-16 US disclosed
US-20050222168-A1 Beta-carboline derived guanidine alkaloids, tiruchenduramine COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-10-06 US disclosed
US-20050221415-A1 Method of assay with sulfonic acid compound and nitro compound ARKRAY, INC. (JP) 2005-10-06 US disclosed
EP-1556023-A1 NUTRITIONAL OR THERAPEUTIC COMPOSITIONS Crum, Albert B. (US) 2005-07-27 EP disclosed
EP-1531855-A2 TREATMENT OF BONE DISORDERS WITH SKELETAL ANABOLIC DRUGS Osteotrophin LLC (US) 2005-05-25 EP disclosed
WO-2004026289-A1 NUTRITIONAL OR THERAPEUTIC COMPOSITIONS THE PROIMMUNE COMPANY (US) 2004-04-01 WO disclosed
WO-2003059291-A2 TREATMENT OF BONE DISORDERS WITH SKELETAL ANABOLIC DRUGS OSTEOTROPHIN LLC (US) 2003-07-24 WO disclosed
US-6592908-B1 Nutritional or therapeutic compositions CRUM ALBERT (US) 2003-07-15 US disclosed
CN-1370173-A Isomeric fused pyrrolocarbazoles and isotetralones CEPHALON INC (US) 2002-09-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070025948-A1 Dilution-type sterilizer composition HAO2, ALPG, CHCHD6 EPHX1 3557/4885ALDH1A1 602/4885CYP1A2 422/4885
US-20220023198-A1 ORAL SOLUBLE FILM CONTAINING SILDENAFIL CITRATE PDE12, SORD, PDE5A EPHX1 1408/4885ALDH1A1 302/4885CYP1A2 795/4885
US-20050222168-A1 Beta-carboline derived guanidine alkaloids, tiruchenduramine GANAB, GBA3, TREH EPHX1 2837/4885ALDH1A1 927/4885CYP1A2 3538/4885
US-11179331-B1 Oral soluble film containing sildenafil citrate PDE12, SORD, PDE5A EPHX1 1408/4885ALDH1A1 302/4885CYP1A2 795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.