Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL29450224 | 1.00 | KMT2A (0.46) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL29506784 | 0.98 | KMT2A (0.47) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL3144433 | 0.98 | KMT2A (0.47) | KMT2AMAPTMEN1THRBRECQL | |
| Hydrochloric Acid SCHEMBL5405589 | 0.96 | KMT2A (0.46) | KMT2AMAPTMEN1THRBRECQL | |
| Bromide SCHEMBL29525346 | 0.96 | KMT2A (0.46) | KMT2AMAPTMEN1THRBRECQL | |
| Bromide SCHEMBL5405629 | 0.96 | KMT2A (0.46) | KMT2AMAPTMEN1THRBRECQL | |
| Acetaldehyde SCHEMBL28919189 | 0.89 | MAPT (0.46) | KMT2AMAPTMEN1THRBRECQL | |
| Sulfuric Acid SCHEMBL5413351 | 0.88 | KMT2A (0.48) | KMT2AMAPTMEN1THRBRECQL | |
| Sulfuric Acid SCHEMBL5413355 | 0.88 | KMT2A (0.48) | KMT2AMAPTMEN1THRBRECQL | |
| Sulfuric Acid SCHEMBL5406406 | 0.88 | KMT2A (0.48) | KMT2AMAPTMEN1THRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111056985-B | Partially cyanine derivative fluorescent probe and preparation method and application thereof | 广州大学 | 2022-12-27 | — | — | CN | claimed |
| CN-114315733-A | Photoinduced cell covalent labeling fluorescent molecule, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-04-12 | — | — | CN | claimed |
| CN-114106004-A | Chelate zinc ion fluorescent probe and preparation method and biological application thereof | 福建师范大学 | 2022-03-01 | — | — | CN | claimed |
| CN-114044780-A | Zinc ion near-infrared fluorescent probe and preparation method and application thereof | 福建师范大学 | 2022-02-15 | — | — | CN | claimed |
| CN-113736282-A | Synthesis and application of indole hemicyanine structure photochromic dye | 三峡大学 | 2021-12-03 | — | — | CN | claimed |
| CN-110161005-B | Fluorescent carbon dot for detecting cell activity, preparation method and application thereof | 郑州大学 | 2021-08-27 | — | — | CN | claimed |
| CN-110041305-B | Indole hemicyanine fluorescent probe, preparation method and application in cyanide ion detection | 三峡大学 | 2021-05-18 | — | — | CN | claimed |
| CN-109053549-B | Two-photon fluorescent probe for positioning mitochondria to detect viscosity and synthetic method and application thereof | 济南大学 | 2020-08-11 | — | — | CN | claimed |
| CN-111056985-A | Partially cyanine derivative fluorescent probe and preparation method and application thereof | 广州大学 | 2020-04-24 | — | — | CN | claimed |
| CN-110317158-A | A kind of synthesis of double-mode optical probe indoles iodide and its detection to uns-dimethylhydrazine | 兰州大学 | 2019-10-11 | — | — | CN | claimed |
| EP-0873744-A2 | Use of heterocyclic carbonyl compounds for dying keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-0873746-A2 | Dyestuff for keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-0873743-A2 | Use of benzylidene-ketones for dyeing keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-0615856-B1 | Recording sheets containing tetrazolium, indolinium, imidazole and imidazolinium compounds | XEROX CORP (US) | 1997-05-14 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-5457486-A | Thermal printing | XEROX CORPORATION (US) | 1995-10-10 | — | — | US | claimed |
| EP-0615856-A1 | Recording sheets containing tetrazolium, indolinium, imidazole and imidazolinium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |